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… about natural products and the science and scientists of secondary metabolism. Welcome back. This will be episode 12 … ZIEMERT: Big picture, I want to understand how secondary metabolites evolve– who makes them, how do they spread, why do they spread in a certain way from one bacteria to another, how do they change then, and why are …

… between two genomes,  we use it to identify and classify bacteria and archaea as well as gain insights into the … of Earth’s microbiomes. Nat Biotechnol 39 , 499–509 (2021). https://doi.org/10.1038/s41587-020-0718-6 I-Min A … R.A. et al. Cryptic inoviruses revealed as pervasive in bacteria and archaea across Earth’s biomes. Nat Microbiol 4 …

… Roux, S., Paul, B.G., Bagby, S.C. et al. (2021) Ecology and molecular targets of hypermutation in the … viral infection cycle in wild populations of green sulfur bacteria with long standing virus-host interactions. ISME J. … revealed as pervasive in bacteria and archaea across Earth’s biomes. Nature Microbiology. 4, 1895–1906. …

… about natural products and the science and scientists of secondary metabolism. Welcome back for our second season of … se, how do you see genome mining and looking for secondary metabolites in the genome as relevant to the JGI mission? … often live in symbiosis with plants and might actually be producing molecules that are helpful to the plants. And so, …

… FY22 and later through the Community Science Program (CSP), Facilities Integrating Collaborations for User Science … Proposals accepted before FY22 are transitioning away from producing use-restricted data. JGI proposals typically … for which JGI has not yet received samples as of Sep 30, 2021 are subject to a 2-year embargo to maintain the …

… interview chairs and I talk about SMC – which is the new Secondary Metabolism Collaboratory data portal I’ve been … Scripps. So we’re looking at biosynthesis of marine fungal metabolites. We’re also looking– now we’re started a newer … has been doing work in secondary metabolism. The very first CSP I ever worked on back in Brad’s lab, we talked about it …

… I’ve been working with him on as an exploration into the secondary metabolism of some more novel marine bacteria. You … seems hard to believe in retrospect. BILL FENICAL: Well, in 2021, absolutely hard to believe. But when you go way back, … do the full genomes for us. So fortunately, the secondary metabolite component of the JGI, people are interested in …

… and pathways. The JGI Metabolomics Platform delivers rich metabolite profiles from diverse biological and … At JGI, in-depth molecular profiles are generated for metabolites extracted from a variety of experimental … types of environments (e.g. soil, lake).  A wide range of metabolites are identified using LC-MS/MS methods optimized …

… Prodcast,” a podcast about the science and scientists of secondary metabolism.  DAN: Hey there. This is Dan again, … in Nature and Medicine.” It’s obviously focused more on the bacterial side of the field, and it’s a little hard to find … the genes that code for the proteins that produce secondary metabolites. Do you recognize this? DNA 🡺 RNA 🡺 Protein …

… about natural products and the science and scientists of secondary metabolism. Hey there, and welcome back to Natural … on synthetic biology of engineering gene expression in bacteria – however, the professor was actually quite … gene clusters. And also correlating these gene clusters to metabolites. So knowing, OK, which metabolites are actually …

… Prodcast,” a podcast about the science and scientists of secondary metabolism.  DAN: Hey there, and welcome to the … chemical compounds that you find in plants, fungi and bacteria, basically all living things. When your crazy Aunt … Nigel Mouncey, started and leads the JGI’s Secondary Metabolites Science Program, which I was hired into, and my …

… about several different pieces of her work, including bacterial quorum sensing and its effects on regulation of … pathways, which led her to a successfully funded JGI CSP project. And we also got to talk about work at her … products. BETSY PARKINSON: Yeah. DAN: Are you familiar with Tiny Earth? BETSY PARKINSON: I am familiar with Tiny Earth, …