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Synthesis
The Joint Genome Institute's DNA Synthesis Platform capabilities support researchers exploring how to … group and focused on new technologies and optimizing tools — including strain engineering — to make them more … Synthetic Biology Informatics Group : a team that develops data science tools for workflow management and novel …
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Natural Prodcast Episode 24: Jackie Winter and SMC
SMC – which is the new Secondary Metabolism Collaboratory data portal I’ve been working on with my colleagues Drew … Doering and Bryce Foster and too many others to name at JGI for the last two years or so. SMC is now released and ready … of always working on natural products but just different tools and how to really access and manipulate these pathways …
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Natural Prodcast Episode 18: A CSP Primer
It’s been a while, but Natural Prodcast is back again for another round of episodes. If you stick around for the … did those sequences go? Like, what are the other scientific tools we offer people? TANJA WOYKE: Yeah. Also a really good … the submission. And so there’s specific areas that they’re assessing, which scientific merit is key. Is it relevant to …
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Natural Prodcast Episode 10: A Primer on Genome Mining
… and scientists of secondary metabolism. Welcome back for our second season of Natural Prodcast. This first … now, just because of the ways that we can generate data. So, obviously, it’s very apparent to us here at the … We compare those sequences with our sequence. The premier tool for that these days, the one that pretty much everybody …
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Natural Prodcast Episode 1: The Primer, Part 1
Takemura, whose voice you’ll hear in a minute – we work for the US Department of Energy Joint Genome Institute, or … so now here at the JGI, I work with all of the sequencing data that the JGI produces to try to find and identify … how funny, you know, the human endeavor of understanding nature is: we want to categorize things into these arbitrary …
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Natural Prodcast Episode 7: Ben Shen
… of secondary metabolism.  DAN: Hello, and welcome back for Episode 7 of the Natural Prodcast. It’s been about a … fundamentals. What is beautiful for natural products is nature! Nature does this sort of – if you think of nature as … so everybody, readers of the library, can come to our databases and look for the specific information they are …
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Natural Prodcast Episode 14: Nigel Mouncey
… … DAN: Hello, everyone, and Welcome back for Episode 14 of Natural Prodcast . There’s been a lot … using these together along with all of our computational tools to really build out much more of an integrative … heard me speak recently have heard me talk about the new data portal that we’re building. And I’ve been eager to …
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Natural Prodcast Episode 13: Francisco Barona Goméz
Mexico, and an incredibly bright guy who’s been thinking for a long time about the evolution and natural products … him about more recent work like ActDES, which is a curated database of actinobacteria for evolutionary studies, and … the Nature Chemical Biology — or early this year– this new tool that we call CORASON, which is basically an acronym to …
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Natural Prodcast Episode 8: Eric Schmidt
… of secondary metabolism.  DAN: Hey there and welcome back for Episode 8 of Natural Prodcast. This week, we have our … learn how to make peptides, rationally. We’d find these tools, we’d understand them, and we’d apply them. And so, I … proteins interact with each other. There’s a lot of leading data from excellent groups about specific interaction …
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Natural Prodcast Episode 3: The Primer, Part 3
… recommend David Hopwood’s book called  “Streptomyces in Nature and Medicine.” It’s obviously focused more on the … it’s a little hard to find in print, but we live in the information age and the ebook version is available at most … probably been since the last decade. We have a lot more data. Obviously, there’s been a lot of sequencing going on, …
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Natural Prodcast Episode 20: Brian Bachmann
I wanted to tell you about in this introduction. First and foremost, our interview this week is with Professor Brian … a postdoc and went to industry to see what they had, what data they had. DAN UDWARY: And they had a lot of data for … an undergraduate and not succeeding and still using all the tools from mechanistic enzymology to natural product …
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Natural Prodcast Episode 4: Nancy Keller
… to Natural Prodcast! This is episode 4! From here on out, for a while, we’re going to be presenting some conversations … the feed, the secondary metabolism field has been dominated for … well, as long as I can remember, by bacterial … Aspergillus was pretty good, but, you know, just from a data standpoint, just figuring out introns and dealing with, …
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