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Mining Metagenomes for Cas Proteins
… acids (aa) in size, half that of previously known class 2 CRISPR enzymes that are typically 950—1400 aa. They were initially identified by searching for Cas12d homologs across IMG/M’s assembled metagenomic data. It … out that some of these were shorter than the typical Cas12d proteins and were also found next to cas1 genes. Further …
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JGI@25: Tracking & Subduing the Plague of California’s Oak Woodlands
… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements that … 1;313(5791):1261-6. doi: 10.1126/science.1128796 Science News of the Day: Stokstad E. Genetics. Genomes highlight …
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Improved Draft Genome Sequence of Microbacterium sp. Strain LKL04, a Bacterial Endophyte Associated with Switchgrass Plants
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Natural Prodcast Episode 19: Bill Fenical
… seems hard to believe in retrospect. BILL FENICAL: Well, in 2021, absolutely hard to believe. But when you go way back, … discovered this and it got developed in somewhere around 2004, I guess, something like that, and now, 2021, it doesn’t …
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Secondary Metabolites Program
… Development of cell-free based expression platforms: Only 10-20% of BGCs are expressed under standard laboratory …
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Examples: Successful LOIs & Submissions
… CSP Large-Scale LOI #2 … FICUS Example #2 …
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Data Ecosystem
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Tanja Woyke Elected to American Academy of Microbiology
… (AAM) ! She is among the 68 new Fellows in the Class of 2020, selected from 118 nominees. The selection process for … the AAM Fellows in this cohort. Go here for the full AAM news release. Woyke is also one of the organizers for the …
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Silver age of GOLD introduces new features
… The JGI’s Genomes OnLine Database celebrates 25 years as a vital resource for data contextualization The Science Since its launch 25 years ago, the  Genomes OnLine Database has matured from … samples and is the only resource in the world with nearly 200,000 curated environmental samples with canonical names.  …
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New and Improved: Eucalyptus Reference is Now Accessible
… | Genetics , with significant advances compared to the 2014 Eucalyptus grandis reference genome that has been … have relied on the E. grandis reference genome published in 2014 by a team led by University of Pretoria scientists with … genome assembly and annotation. Genome contiguity of the 2025 phased reference and 2014 diploid genome reference was …
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Events
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JGI Portals
… Portal was replaced with the Data Portal and sunset in 2026. The Genome Portal was designed to provide unified access … and analytical tools for all JGI sequencing projects. In 2021, the JGI launched the Data Portal to eventually replace …
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