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FY 2025 DOE Metrics Sequencing Quarter Total Bases (Trillions) … is based on 98% of the total available hours.   FY 2024 DOE Metrics There were 2,456 unique* JGI users in FY2024 , which includes Principal Investigators …

… to the California gold rush. And we’ll talk about a new JGI paper that’s just come out where I got the chance to do … genome mining is, if I want to explain that to someone who doesn’t know much about genetics or anything else, science … out http://naturalprodcast.com for show notes with links to papers and other learning resources. Relevant links  The …

I’d encourage you to come check out the links to some cool papers in the show notes, which you can always find at naturalprodcast.com or through the JGI website at jgi.doe.gov . There’s a lot more to talk about there, and I’ll …

… describe. [ Go here to learn more about Tiny Earth and the JGI’s role in the project by watching Amanda Hurley’s … all over the world in the next couple of years. DAN: What does it take to become a hub? MARC: We’re still trying to … Mark, which is [something you’ve] published some great papers [on] recently – on evolution of biosynthetic gene …

… with my co-host Alison Takemura, who’s moved on from JGI to do real journalism, and we wish her all the best. … what are you going to do. So, you probably know that “DOE” is the United States Department of Energy, which is a … of those individuals. Also, if you need a “Materials and Methods” section, we can provide that information as well. …

… think his energy is infectious. DAN: I’ll say up front that JGI recently started collaborating with Ben and his group to … fundamentals. What is beautiful for natural products is nature! Nature does this sort of – if you think of nature as a scientist, …

I didn’t know how to get towards that.  Organic chemistry doesn’t really help with getting to something other than the … do when you’re exploring your systems. Because I think the JGI has a little bit of a different approach. We don’t … chemistry happening.  And so one of the recently published papers was about doing this with human pathogens. And I had …

… things I want to make sure that we talk about. You have a JGI project going with us that we want to talk a little bit … contain chlorine. And we saw this and started publishing papers. And one thing led to another. And we started … concentration of calcium, and so on. And what difference does it make? The idea that you would say marine life make …

… if they’re not stored properly. And so I read lots of your papers when I was in graduate school.    NANCY: Forced to!   … in that area?   NANCY: Oh, well, I love fungi, okay, this doesn’t even have anything to use natural products … actually, everything is funding, right, isn’t it? I thank JGI for sequencing a lot of fungi. But the thing with them – …

… natural products chemistry, and he has a project with the JGI to synthesize the genes for and explore the chemistry of … Alison is no longer with us… She’s alive! She just doesn’t work for JGI anymore! [LAUGHTER] AARON PURI: Yeah. … JGI is we identified using some different computational methods a bunch of different syntheses that make quorum …

… state of things, and what we’re hoping to accomplish at JGI in this area. If this series of podcast episodes has … recommend David Hopwood’s book called  “Streptomyces in Nature and Medicine.” It’s obviously focused more on the … we recognize and sticking another piece in, that usually doesn’t work, or if it does work, it doesn’t work as well, …

… and also talk about some of the great science that he does. So welcome to the show Paco Barona-Gomez from the … product biosynthesis overall have had read some of their papers and one seminal book, which talks about this idea of … thing. Another way to approach it is more related to what JGI does, which is sequence genomes. And we just published …