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… genome program. And I’m a scientist here. And have been for 18 years. (LAUGHS) DAN UDWARY: All right. Easy start. What … where smaller proposals may be a fit. Still not 20 many microbes. We still we work in plates, right? We’re a high …

… about microbiology and natural products from the Great Salt Lake, and you’re going to learn, like me, what a “haboob” … in this hypersaline environment, which can range from 8% to 28% salinity. We have toxic metals, so these … there a way to do that? DAN UDWARY: Well, so there’s good news and bad news on that. So one of the things that we’re …

… put into antiSMASH after downloading it was isolated from Lake Washington. So it’s really interesting that it was … learn as much about it as possible starting with we picked 183 of them. And we sent that list to the Joint Genome …

… of novel bacterial, archaeal and eukaryotic microbes and viruses in environmental sequence data. We use … host interactions through global metagenomics. Nature. 578 (7795), 432-436 Schulz et al. (2020) Advantages and limits … binning of a giant virus. mSystems. 5 (3) Schulz et al. (2018) Hidden diversity of soil giant viruses. Nature …

… variety of experimental samples, including organisms (e.g. microbes, fungi, plant), media in which they grow, as well as different types of environments (e.g. soil, lake).  A wide range of metabolites are identified using …

… product reports on the evolution of genome mining and microbes with Mohammad Alanjary and Tilmann Weber to be a … Europe. So if there are any kind of dated references to the news, that’s why. But it was a really fun conversation. And … soil. But we also have, in collaboration with other people, lake sediments. We have microbiomes from different …

… plants’ chemistry ever since the isolation of morphine, 1870 or something like that. And so people were well aware … you think about the fact that, when plants and animals and microbes evolve, they evolve to make molecules that improve …

Microbiomes. Nature  Biotechnology . 2020 Nov 9. doi: 10.1038/s41587-020-0718-6) The GEM catalog expands the bacterial and archaeal … Microbiomes” paper is here . Read the associated JGI news release here . Software we discussed, used for genome …

But the structure of which was not known until the middle ’80s. And then the first time we saw the structure that Dan … So I wanted to ask you also about – because you were in the news recently – TSRI has acquired the Pfizer strain … is a geographic distribution. So they were collected from 108 countries and regions. So, this is really collected from …

… it’s very situational. And every microbe is a special snowflake. So… ALISON: Yeah, I mean, would you say that all … new. I joined as the lead on the genomic side about 6, 7, 8 months ago, and our metabolomics expert was around the … that’s really popped up at funding agencies and the popular news recently because a lot of soldiers in the Iraq and …

… from lignin left over after biomass processing. Great Lakes Bioenergy Research Center , led by the University of …

… never forced it on me, but we always had these scientific news magazines lying around at home. And I would just pick … NIGEL MOUNCEY: Yeah, so we put out a strategic plan in 2018. And in building that plan, we thought about secondary …