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… also twofold but for different reasons to learn about how nature builds molecules because nature does this with such elegance And also to take … of sequences that we worked with JGI on, and those are ancestral protein sequences. And so starting from some of …

I wish we had snow. And [laughs] kids back in school from home, not back at school. So, yeah. So there’s been a lot … did? What we’re talking about here is a paper published in Nature Biotechnology, titled ‘A genomic catalog of Earth’s … Nayfach S et al. A Genomic Catalog of Earth’s Microbiomes. Nature  Biotechnology . 2020 Nov 9. doi: …

DAN: Oh, I did not know that. That's cool. JACKIE: But nature can do this. BETSY PARKINSON: But nature can do it much better than a lot of synthetic … bring in their soil. They plate it, and then they take it home. DAN: Got it. BETSY PARKINSON: And the Petri dish. DAN: …

… feet of glacier core that we field sterilized and brought home. That was unique. And so we have done a little bit of …

… understand the chemical diversity and chemical utility that nature has to offer us. I found this conversation really … broader questions about how chemistry is diversified in nature, and when it is not diversified and why? Where are … Which bits of chemical space are you never going to find in nature? And are any of those bits of chemical space relevant …

January 2020 in San Diego. San Diego, of course, is the “home turf” of my post-doctoral mentor, Brad Moore, who has … of those, you know, early-on reactions that we see. And so nature does that as well. But it does it with exquisite … so, for us, we’re fascinated by understanding the logic of nature and how it can control something that a chemist is …

… technologies or uses or applications– are the evolutionary nature of these compounds. At the end of the day, all the … he’s not mutated under those circumstances. Whereas the nature of the evolutionary force, the selection there is … we didn’t realize something that I think is the main take-home message of this long review –that is more like a, not …

… fundamentals. What is beautiful for natural products is nature! Nature does this sort of – if you think of nature as a scientist, nature is doing science, way longer …

… so we can train them to take the course back to their home institutions. ALISON: Oh, cool. So is that how it … we have no idea what natural products are doing in nature. And it’s a really difficult thing to unpack … the system. Now, that’s probably not true across all of nature, but it’s a simplifying assumption that we wanted to …

… secondary metabolite peptides. And there are two ways that nature does this. The more well-known secondary metabolism … of Illinois, and many others who are very collaborative in nature, I think, led to kind of the definition of our field … can more predictably make compounds. And so that relates to nature very directly because natural evolution tells you …

… mom of four kids now so ranging from 8 to 17 in age, so my home life is very busy. And I’m also a pet mom of a mini pig … the fact that many of our modern medicines are derived from nature, and in many cases from plants. And so I think of nature as giving us the gift of blueprints to interesting …