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… who also do genome mining. We’ve got a great, fun bunch of little shows lined up, and I’m really looking forward to … searches, but antiSMASH took, basically, all of the known things that were out there and created some good rule … come from all kinds of disparate environments. There’s some marine. There’s some soil samples. There’s human gut …

… of Oceanography in San Diego. Bill is a pioneer of marine natural products, getting into the ocean and looking … You have a JGI project going with us that we want to talk a little bit about. It’s sort of early stages. But I think … the ocean. And I would point out there was almost nothing known, absolutely nothing known, which was exciting but also …

… Professor Eric Schmidt, from the University of Utah. I’ve known Eric for a long time – we worked together on Aflatoxin … modified Peptides.” You’ll have to use your imagination a little bit to really make that make sense as an acronym, but … grade list of goals in life: on that list are being a marine biologist and being a chemist, and it’s actually …

… end, we somehow have the big goal of making that process a little more effective than it is now. Or a little more– … quality. Yeah, for sure. NADINE ZIEMERT: Yeah, Dan… it’s a marine actinomycete bacterium. So they look kind of like … obligate marine. There’s so far no species or no strains known that really grow in freshwater. But they’re actually …

… well-integrated across JGI departments to ensure a robust offering of sequencing capabilities and products to our users. This includes scaling the technologies and enabling state-of-the-art sample processing and sequencing capabilities. … An assay used for profiling transcription factor binding sites across entire …

… The central mission of the JGI’s Genomic Technologies department is   ensuring … .  Many users rely on a multifaceted combination of genomic, transcriptomic, proteomic, phenotypic, … To meet these needs, the JGI deploys state-of-the-art sequencers and platforms dedicated to synthesis, single-cell …

… Prodcast, and this will be episode 11. This continues our little sprint on genome mining. In the last episode , Alison … forces instead of to make two competing tools. If we had known about your tool, Dan, we would have contacted you as … then got funded to work for two years at the Max Planck for marine microbiology in Bremen, Germany. And I wanted to work …

… Natural Prodcast . There’s been a lot going on, so I took a little break, but I’m hoping that from here I can get back … been working in the Department of Energy. I really wasn’t known to them and they weren’t known to me.  DAN: Sure.  … Yeah. So every year we hold this meeting and we really attract just world renowned speakers to talk about the …

… wouldn’t it be cool to look at these– it was actually marine invertebrates there– but look at these things in the … been talking to a few different people about. So tell us a little bit about your perspective on that kind of technique … we had to try and figure out what was there. Like, was it a known metabolite? Was it something new? And we could only do …

… The Metagenome Program uses advanced sequencing technologies to decode the genomes of microbes in their natural environments. This work … drive innovations that could advance our understanding of Earth’s ecosystems. … Program focuses on the high-throughput sequencing of microbial communities to uncover the complex interactions …

… Research in the Eloe-Fadrosh group focuses on using genome-resolved metagenomic approaches to identify and … develop computational approaches to sift through thousands of metagenomes for signatures of viruses and novel microbial lineages, and reconstruct … Our research focuses on the assembly of metagenomic sequence data into microbial genomes, which …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … useful! DAN: Among many other things, Ben is maybe best known as an expert in enediynes – that’s a class of natural … out better ways to produce them. Do you want to talk a little bit about that project and how that got started? BEN: …