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UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast, a podcast about natural … to the California gold rush. And we’ll talk about a new JGI paper that’s just come out where I got the chance to do … important to us. ALISON TAKEMURA: Yeah, and actually, that makes me think about how we can kind of use an extended …

Udwary: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast, a podcast about natural … years of antiSMASH, we only made updates for every NAR paper that we wrote about, like, a new version of antiSMASH. … are able to find your gene cluster and cite it. But it also makes the data usable for people who want to do the next …

… in the early 2000s called Ecopia, which was a very early genome mining company, back when DNA sequencing of natural … I’d encourage you to come check out the links to some cool papers in the show notes, which you can always find at … I did not know what I was doing. BRIAN BACHMANN: Yeah, that makes two of us. DAN UDWARY: So the audio quality was …

Oh, goodness. I mean, if you were to find my scientific papers, that would be Katherine. Dan Udwary: Right. Kate … was really before– or kind of around about when the first genome sequencing was done. But natural products– marine … is a great website name, and also extremely well-organized, makes doing research on a person very easy. Kate Duncan: …

You’re listening to the US. .Department of Energy Joint Genome Institute’s “Natural Prodcast,” a podcast about the … it’s in our screen, and we’re seeing hits to that. So that makes us excited. But we’re also excited about antibiotics … Mark, which is [something you’ve] published some great papers [on] recently – on evolution of biosynthetic gene …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a podcast about the … I also want to emphasize, I think that’s the part that makes me really excited. You know, you asked, “What are the … at several natural product enediyne structures, Ben’s 2015 paper on genome mining for enediynes is one of my favorites. …

UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast– a podcast about natural … podcast for you. A lot of this is based on a really great paper that came out in 2020 where this is all explained in … about a plant and a microbe interacting very stably. So it makes sense that you end up having a very unique on one …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a podcast about the … get into seaweed, robots, algae, and biocatalysis — and he makes fun of me a lot, though I actually edited most of that … underwater vehicles. Brad: You did not! Alison: I did, like 2016, I think. Yes, it was just so funny to hear how they’re …

… and there’s an audio version, read by Cassandra, and the paperback version will be available in June. You can get … the fact that many of our modern medicines are derived from nature, and in many cases from plants. And so I think of … it’s not that easy. There are still not that many plant genomes, certainly nowhere close to bacterial kinds of …

… almost never Actinomycetes. And so when we look at their genomes we don’t get the same kind of information that we … chemistry happening.  And so one of the recently published papers was about doing this with human pathogens. And I had … out how to show this data and to do it in a way that makes sense. And I always call this the needle in the …

… off today with my interview with the Director of the Joint Genome Institute and head of the Secondary Metabolites … insight. And I really thought about that, but that totally makes sense. That’s a big part of what I enjoy about being … And I will put it in the show notes along with the CRAGE papers and some spinosyns.  NIGEL MOUNCEY: Right, Yeah. So …

… enzymes to do chemical reactions. Obviously, in my work, in genome mining, we have an awful lot of crossover, where us … also twofold but for different reasons to learn about how nature builds molecules because nature does this with such … you can’t destroy, we’ll pick that one. DAN UDWARY: That makes sense, yeah. ALISON NARAYAN: Because we want everyone …