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… going to talk about JGI’s Community Science Program , or CSP, which is the main mechanism by which users work with … proposals that are really multifaceted, that do request a diversity of the different capabilities that we have, that … benefit that one PI, but that have utility more broadly across a group of scientists, across the scientific …

Program focuses on the exploration of secondary metabolites across bacteria, fungi, algae and plants. These molecules, … program aims to tap into the largely unexplored biochemical diversity within secondary metabolites, expanding their … of BGC size and complexity, BGC sequence composition, metabolic similarity & compatibility, and signatures of …

… emphasis that are listed in the call and leverage the diversity of JGI technical and analytical capabilities. All … is no cost to the user and no granting of funds. … For the CSP Large Scale call, a Letter of Intent (LOI) is required …

… be hearing about microbiology and natural products from the Great Salt Lake, and you’re going to learn, like me, what a … lake-effect snow from Great Salt Lake too. So that moves across, and I’m looking at my window because if it starts … has been doing work in secondary metabolism. The very first CSP I ever worked on back in Brad’s lab, we talked about it …

The CSP New Investigator Call is for investigators and research … PIs cannot have been lead PI on any previously accepted JGI CSP or FICUS proposal.   Competitive projects will provide … a novel approach or form the foundation for a large-scale CSP proposal submission. Sequence requests should not exceed …

The CSP Functional Genomics call is to enable users to perform …

… target is based on 98% of the total available hours.   FY 2018 DOE Metrics There were 1,882 unique* JGI users in FY2018 , which includes Principal Investigators (PIs), Co-PIs, … % of Goal Goal (hours)** Actual Total Actual % Goal FY 2018 Total 200,000 225,299 112.6% 8,584 8,688 101.2% Q1 2018 …

… research.  These efforts include exploration of the global diversity of alternative genetic codes (Science 2014), … hosts (Nature 2016, Science 2017, Nature Microbiology 2018), discovery of new genes with important … new CRISPR-Cas types) (Nature Communications 2017, Science 2018, Molecular Cell 2019) and massive reconstruction of …

Large-Scale Call, as well as successful submissions to our CSP New Investigator, CSP Functional Genomics, and … in a cosmopolitan and abundant soil bacterium: genetic microdiversity or core metabolic flexibility? … Microbial contributions to soil …

… and should generally conform to the guidelines for our  CSP Large Scale call .  Process Proposals may be submitted … byproducts from lignin left over after biomass processing. Great Lakes Bioenergy Research Center , led by the University of …

… still persists to date. Research Team    … Phylogenetic diversity estimates show that the gap between cultivated and … anchors for metagenomes studies.  While uncovering the metabolic potential of uncultivated lineages is of high … the Hungate1000 Collection.” Nat Biotechnol 36(4): 359-367 (2018). Woyke T ., Doud D. F. R., Schulz F. The trajectory of …

… is that you could, therefore, expect a lot of chemical diversity. So many compounds will fulfill the same function. … about it, the only way a primary metabolite or a primary metabolic pathway is good for anything, it is if the final … or specialized metabolism, what we are often coming across is very complicated pathways with many, many enzymes, …