Search

… of secondary metabolite biosynthesis: We have developed Regulon Identification by in vitro-sequencing (RIViT-seq) to identify RNA polymerase-sigma factor targets, …

RIViT-seq technology could speed up associating transcription factors with their target genes. The Science Regulons are a group of genes that can be turned on or off … demonstrated the efficacy and potential of regulon identification by in vitro transcription-sequencing …

The JGI’s Microbial Program focuses on using cutting-edge sequencing, annotation and analysis … to explore the vast and diverse world of microbes. Studying bacteria and archaea, including those associated with …

The Metagenome Program uses advanced sequencing technologies to decode the genomes of microbes in their natural environments. This work encompasses bacteria, archaea, and micro-eukaryoes, along with their …

… saw a potential mechanism for why there would be this streamlining? NADINE ZIEMERT: Yes, and just how one certain … I think. DAN UDWARY: Yeah, and that was a JGI Community Sequencing Project. You’re right, yeah. NADINE ZIEMERT: Yes. … existing technology. And a lot of that was around chemical identification technology, mass spec, NMR. And we talked a …

… collaborative user projects, the JGI’s Plant Program delves into the natural world’s potential to address global … into chemical energy — and its implications for carbon sequestration, renewable energy and agricultural … these species. The pangenomes enable the exploration and identification of small and large structural variation — …

… fantastic diversity of cell types and associated organisms, including fungal and bacterial symbionts, detrimental microbial pathogens, and … and spatial transcriptomics barcode-based genetics (RB-TnSeq), and computational genomics to better understand the …

… to unlock their potential for bioenergy, environmental sustainability, and bioproducts. By sequencing and analyzing the genomes of these organisms, the … and engineered strains. This approach allows for the identification of key functional traits that have direct …

DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s … more than 50,000 genomes that we derived from meta-genome sequences. As always, you’ll find transcripts and show notes … in one package so that it opened up secondary metabolism identification to anyone who wanted to do it. And it’s been …

… of natural products, Professor Bill Fenical from Scripps Institution of Oceanography in San Diego. Bill is a pioneer … into the secondary metabolism of some more novel marine bacteria. You know, I first met Bill as a postdoc working … forward to seeing the data when it finally gets off the sequencers. The pandemic has obviously slowed JGI down a …

… … Dan Udwary: You’re listening to the Department of Energy Joint Genome Institute’s … about the basics of genome mining, which is using DNA sequence to identify and interpret biosynthetic, secondary … to my submission, they were saying that natural product identification– biosynthetic gene cluster identification was …