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… in the Woyke laboratory focuses on the utility of single-cell methods to access genetic material of uncultivated taxa … The “Great Plate-Count Anomaly” first described by Stanley and Konopa in 1985, which highlights our skewed … in the strongly biased representation of sequenced genomes in the public domain, the bulk of which belong to …

… technology in order to enhance the quality of single-cell genomes and directly link functional information with … DNA amplification, and sequence analysis to recover the genomes of uncultivated microbes. We also apply labeling …

… data and serving them to users via the Integrated Microbial Genomes & Microbiomes (IMG/M) system. Research Team    … The … computed for nearly 28,000 bacterial and archaeal genomes. By clustering genomes based on their pairwise AF and ANI … ANI is used to ascertain the species specificity of single cells and genomes extracted from metagenomes, and also as a …

… people all over the word who have a common interest, united by natural products, DAN: You guys have put together a … is always associated with toxicity, basically, killing cells. ALISON: Right, because they’re so reactive. BEN: … well. One is to do DNA sequencing. So upon sequencing many genomes, now we don’t have to, as in the past, go randomly …

… are complex organisms that harbor a fantastic diversity of cell types and associated organisms, including fungal and … in how plants self-organize, influence, and are influenced by microbial partners. We use a variety of genomics-powered … tools to study this complexity, including single-cell and spatial transcriptomics barcode-based genetics …

… use multi-omics (metagenomics, metatranscriptomics, single cell genomics and phylogenomics) and machine learning to … Schulz and Horn (2015) Intranuclear bacteria: inside the cellular control center of eukaryotes. Trends in cell biology. 25 (6), 339-346 Schulz et al. (2015) Marine …

… and quality of finished product depend on genome. Selected genomes will be improved based on feasibility and scientific … Assembly, annotation ( IMG/M ), mapping 273/273 Metagenome Cell Enrichments Obtained by physical separation of a biologically relevant unit from …

… great conversations that we’ve already recorded with some excellent scientists, and that’s probably how we’ll continue … search away! If you like these primer episodes, let me know by emailing us to [email protected], or on twitter @JGI or … they figured out that they could culture the plant cells and produce enough that way in really large like 7500 …

… however they do so under strong constraints exerted by viruses. Research in the viral genomics group aims at … mechanisms involved in virus:host interaction and host cell take-over by viruses, and attempts to evaluate ecosystem-level impacts …

… to cutting-edge capabilities to help advance their science by generating data in three overarching categories: … and further advancing sequence applications, single cell genomics, DNA synthesis, and metabolomics.   … Deputy …

Biology is currently experiencing a revolution brought on by rapid developments in genomics and other omics … 2014), unearthing hundreds of thousands of new viral genomes and their predicted hosts (Nature 2016, Science … types) (Nature Communications 2017, Science 2018, Molecular Cell 2019) and massive reconstruction of genomes from …

… merit, DOE mission relevance, proposed data usage by the applicant/community, and track record of the … synthesis, metabolomics and analysis will be paid for by the Department of Energy’s funding of the JGI. There is … CSP Large Scale call, a Letter of Intent (LOI) is required by the due date printed below. Proposals will be invited …