Further engineering of R. toruloides for the production of terpenes from lignocellulosic biomass

Published in:

Biotechnology for Biofuels 14(1) ( 2021)

Author(s):

Kirby, J., Geiselman, G. M., Yaegashi, J., Kim, J., Zhuang, X., Tran-Gyamfi, M. B., Prahl, J. P., Sundstrom, E. R., Gao, Y., Munoz, N., Burnum-Johnson, K. E., Benites, V. T., Baidoo, E. E. K., Fuhrmann, A., Seibel, K., Webb-Robertson, B. J. M., Zucker, J., Nicora, C. D., Tanjore, D., Magnuson, J. K., Skerker, J. M., Gladden, J. M.

DOI:

10.1186/s13068-021-01950-w

Abstract:

Mitigation of climate change requires that new routes for the production of fuels and chemicals be as oil-independent as possible. The microbial conversion of lignocellulosic feedstocks into terpene-based biofuels and bioproducts represents one such route. This work builds upon previous demonstrations that the single-celled carotenogenic basidiomycete, Rhodosporidium toruloides, is a promising host for the production of terpenes from lignocellulosic hydrolysates. This study focuses on the optimization of production of the monoterpene 1,8-cineole and the sesquiterpene

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