Biochemistry-Guided Prediction of the Absolute Configuration of Fungal Reduced Polyketides

Published in:

Angewandte Chemie - International Edition 60(43) , 23403-23411 ( 2021)

Author(s):

Takino, J., Kotani, A., Ozaki, T., Peng, W., Yu, J., Guo, Y., Mochizuki, S., Akimitsu, K., Hashimoto, M., Ye, T., Minami, A., Oikawa, H.

DOI:

10.1002/anie.202110658

Abstract:

Highly reducing polyketide synthases (HR-PKSs) produce structurally diverse polyketides (PKs). The PK diversity is constructed by a variety of factors, including the

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