Dr. Cheng’s laboratory in recent years has been focusing on developing technologies and laboratory procedures to enable high throughput functional studies of genes. One such example is the development of a semi-automated synthetic DNA assembly and cloning pipeline at the JGI. In addition to help managing activities of the DNA synthesis pipeline at JGI, his group has been developing a generalizable strategy for strain engineering capability to manipulate DNA sequences inside bacteria and yeast cells with no need of prior genetic tools. This technology will further facilitate functional exploration of sequenced genomes.
Research Team
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| Jan-Fang Cheng, PI | Hualan Liu, Project Scientist | Yan Liang, Principal Research Associate | David Robinson, Senior Research Associate |
| JFCheng@lbl.gov | hualanliu@lbl.gov | yliang@lbl.gov | dsrobinson@lbl.gov |
| More about Jan-Fang. | Hualan is leading the efforts of designing genetic tools and procedures to domesticate bacterial species in multiple phyla | Yan is working on in situ microbiome strain engineering. | Dave is working on prokaryotic host engineering. |