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Department of Energy Joint Genome Institute’s Natural Prodcast, a podcast about natural products and the science and … topic in, arguably, my area of expertise, which is genome mining. You’ll hear us talk about what it is, hear me make a … set of MAGs to date. Here, at JGI, we took more than 10,000 metagenomes, many of which were sequenced at JGI, and some …

… in natural environments. Integrating metatranscriptomes and metagenomes can, for instance, deepens our understanding of … of plasmid sequences identified from genomes, SAGs, MAGs, metagenomes and metatranscriptomes. … GOLD is a web resource …

… with important biotechnological applications (e.g., new CRISPR-Cas variants and new CRISPR-Cas types) (Nature … novel methods to enable large-scale comparative analysis, mining and visualization of big data. … Pavlopoulos GA et …

… enables users to validate hypotheses generated from mining genomic data by designing and assembling physical DNA … or MoClo assemblies … Check out our organism-agnostic CRISPR gRNA design tool  … BOOST provides a suite of tools …

Department of Energy Joint Genome Institute’s Natural Prodcast, a podcast about natural products and the science and … in natural product reports on the evolution of genome mining and microbes with Mohammad Alanjary and Tilmann Weber … that easily can identify secondary metabolite pathways in metagenomes, which is still hard to do. We are mining a lot …

Department of Energy Joint Genome Institute’s “Natural Prodcast,” a podcast about the science and scientists of … and his group to work on sequencing, synthesis and genome mining technology to help access complicated natural product … how nature is making compounds, but we are also applying CRISPR technology, anything as genome editing, genome …

… be episode 11. This continues our little sprint on genome mining. In the last episode , Alison and I talked about the … Yeah. There’s so much to do there especially looking at metagenomes. So we’re actually eager soon to also work on … from colleagues at Wageningen University who developed a CRISPR-Cas system for that group of bacteria and that …

… everyone and welcome back to a new session of Natural Prodcast. I’ve got two things I wanted to tell you about in this … early 2000s called Ecopia, which was a very early genome mining company, back when DNA sequencing of natural product … cryo-EM studies to find the binding site. And then we did CRISPR and directed evolution to evolve resistance in the …

… computational approaches to sift through thousands of metagenomes for signatures of viruses and novel microbial …

… software includes: gRNA-SeqRET , an organism-agnostic CRISPR gRNA design tool BOOST , which provides a suite of …

… we have revisited a number of notable achievements that showcase our collaborations and capabilities to enable great … Chemistry to seven. Doudna was recognized for her work on CRISPR-Cas9, technology described by the Nobel Foundation as … JGI’s Microbiome Data Science group led by Nikos Kyrpides , mining the Integrated Microbial Genomics & Microbiomes …

Department of Energy Joint Genome Institute’s “Natural Prodcast,” a podcast about the science and scientists of … DNA sequence – sequences for the genes that code for the proteins that produce secondary metabolites. Do you … to do something that the field refers to as “genome mining”. So, if you can sequence the DNA and actually …