To assist in checking the quality of the microbial genomic DNA sequences generated before they are submitted to the federally funded public archive GenBank, the U.S. Department of Energy (DOE) Joint Genome Institute (JGI) has introduced a quality control tool known as the Gene Prediction IMprovement Pipeline or GenePRIMP. GenePRIMP is described in a paper published online May 2 in Nature Methods and has the potential to become a standard in prokaryotic gene calling, a technique by which the start and end of potential gene coding sequences are identified.
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