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The Fungal & Algal Program explores the vast diversity of fungi … to unlock their potential for bioenergy, environmental sustainability, and bioproducts. By sequencing and analyzing the … on large-scale sequencing efforts that survey the vast phylogenetic and ecological diversity of fungi and algae, …

The Fungal & Algal Program Advisory Committees is chartered by …

… diversity of cell types and associated organisms, including fungal and bacterial symbionts, detrimental microbial … single-cell and spatial transcriptomics barcode-based genetics (RB-TnSeq), and computational genomics to better … strains, whereby they can modulate host metabolism, gene expression and phenotype. We have recently identified …

Program works to uncover the roles of small molecules in biological systems, linking them with genomic data to … metabolomics fuels the discovery  of novel metabolites, genes, and proteins. It also enables exploration of energy … scientists are able to link metabolic activity with gene expression, providing deeper insights into functional …

… percentile*) DNA Synthesis Constructs <5kb in size Single gene or multiple small genes assembled to less than 5kb in … to determine coverage of variants depends on project Fungal Minimal Draft Lower coverage short-read whole genome … alignment files 384/454 Fungal Transcriptome RNA for expression profiling and genome annotation (single …

Machine learning methods were applied on sequenced fungal genomes to classify gene families. The Science As a proof of concept, …

It was unpublished at that point. But people would push out gene clusters maybe once a month at most. Maybe twice a … colors. I mean, where else in nature– and they’re not fungal. Where else nature can you go see colonies of … if you want– if you really want to, you can do heterologous expression. You can do homologous expression techniques and …

… and BiG-SLiCE, and now the BiG-FAM database of biosynthetic gene cluster families. And he tells us about forthcoming … was a proposal on synthetic biology of engineering gene expression in bacteria – however, the professor was actually … are protecting the plants against pathogens. So usually fungal or oomycete pathogens. In this case they worked on a …

… collaborative user projects, the JGI’s Plant Program delves into the natural world’s potential to address global … to regulate Earth's carbon balance, to exploring the genetic basis of how plants have naturally adapted to varied … Centers. The  Plant Gene Atlas initiative develops gene expression catalogs across JGI Plant Flagship …

… growth, provide critical advantages to the organisms producing them, and are often involved in defense, nutrient … conditions, with only a small portion of the biosynthetic gene clusters (BGCs) being expressed. The program works to … pathway analysis, optimization of cell- and cell free-based expression platforms, tools and data for deciphering …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … episode is our conversation with Nancy Keller, a fantastic fungal natural products researcher from the University of … After I got my undergraduate degree, which was in general biology, I joined the Peace Corps. And when I was …

Describing the largest analysis to date of the modified DNA base … on the largest analysis of 5mC distribution across the fungal tree of life to date, involving more than 500 species … that unlike most flowering plants and animals, fungi lack gene body methylation. The analysis revealed that 5mC in …