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The Metagenome Program uses advanced sequencing technologies to decode the genomes of microbes in their natural environments. This work encompasses bacteria, archaea, and … to assess microbial activity across ecosystems.  By studying microbial communities and their interactions, the …

… genomes are critical to serve as phylogenetic anchors for metagenomes studies.  While uncovering the metabolic … ., Ivanova N. N., Kelly W. J. Cultivation and sequencing of rumen microbiome members from the Hungate1000 Collection.” … discovery of biomass-degrading genes and genomes from cow rumen. Science 331, 463-7 (2011). Newton I.L., Woyke T …

Prodcast,” a podcast about the science and scientists of secondary metabolism.  DAN: Hi, again. This is Dan, and you’re … secrete a lot more things than people do…? Although I don’t study people so maybe I’m wrong. But yeah, I mean, because I … them as very small fungi. And this came from a growth on a cow’s cheek. Historically, before antibiotics were common, …

Prodcast,” a podcast about the science and scientists of secondary metabolism.  DAN: Hey there and welcome back for … the end, we took an approach that was kind of a simplified metagenome sequencing approach to pick this system apart.  … crack this case, then that would open up our field to other study. And so it was kind of an early example, to try to …

… … DAN: Hey Marcy!  ALISON: Hey Marcy?  MARCY: Hello. How’s it going?  DAN: Good. … now?  MARCY: Sure. So my lab has really converged on the study of host-microbe chemistry. And the interactions– As … proteobacteria. We find chemistry that’s known, or sometimes novel, but often known, and yet the clusters don’t …

… about natural products and the science and scientists of secondary metabolism. Welcome back. This will be episode 12 of … ALISON TAKEMURA: So Nadine, what got you interested in studying natural products? NADINE ZIEMERT: Like almost … that easily can identify secondary metabolite pathways in metagenomes, which is still hard to do. We are mining a lot …

… about natural products and the science and scientists of secondary metabolism. Hey there, and welcome back to Natural … what was this bacterium, and why did your group want to study it? Marnix Medema: You mean the PhD project that I … primer episode, we talked about genome mining through some metagenome associated genomes. And yes, antiSMASH is …

… … DAN UDWARY: Hey everyone and welcome back to a new session of Natural Prodcast. … hold me accountable and yell at me if I slip again. My JGI coworkers are way too nice to yell at me, so that’s gonna be … just now switching from intermicrobial interactions, studying intermicrobial interactions by imaging interactions …

… and environmental challenges. Oh, the magical world of the cow stomach. Rumen – and its microbes – are really a powerhouse. Rumen … materials, rumen microbes and their enzymes are an optimal study subject that could lead to more sustainable energy …

Prodcast,” a podcast about the science and scientists of secondary metabolism.  DAN: Hey there, and welcome to the first … products into the grain that people are eating in hard times, and becoming ill, and then hallucinating, and … I’m definitely seeing why this is such an important area to study. Okay, what’s your third story?  DAN: The third story …

Prodcast,” a podcast about the science and scientists of secondary metabolism.  Brad Moore, UC San Diego and Scripps … So like, as an undergraduate, I was like, no, I’m going to study architecture. I like making things and designing … the end of last year. Dan: So these are going to be seaweed metagenomes? You’re sequencing everything? Brad: Metagenomes …

… … DAN UDWARY: Hey, everyone. I’ve got a great episode for you here today. We got the … kept looking for open jobs that said, we want a chemist to study the ocean. And I didn’t find a single job … picking up a mushroom. It required, I must say, a couple of times, risking your life in order to find something to work …