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Metagenome Program
The Metagenome Program uses advanced sequencing technologies to decode the genomes of microbes in their … to assess microbial activity across ecosystems.  By studying microbial communities and their interactions, the …
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Sequencing Technologies
The Sequencing Technologies Group applies cutting edge molecular capabilities and state-of-the-art next-generation sequencing to enable biological discovery by the JGI and external …
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Metabolomics Technology Group
Our lab is using mass spectrometry based metabolite profiling to provide direct biochemical datasets to improve our understanding of microbial metabolism. Of particular interest is …
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Single Cell Research Group
… genomes are critical to serve as phylogenetic anchors for metagenomes studies.  While uncovering the metabolic … ., Ivanova N. N., Kelly W. J. Cultivation and sequencing of rumen microbiome members from the Hungate1000 Collection.” … discovery of biomass-degrading genes and genomes from cow rumen. Science 331, 463-7 (2011). Newton I.L., Woyke T …
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Natural Prodcast Episode 12: Nadine Ziemert
… … DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s … ALISON TAKEMURA: So Nadine, what got you interested in studying natural products? NADINE ZIEMERT: Like almost … that easily can identify secondary metabolite pathways in metagenomes, which is still hard to do. We are mining a lot …
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JGI@25: Cow Rumen and the Early Days of Metagenomics
… and environmental challenges. Oh, the magical world of the cow stomach. Rumen – and its microbes – are really a powerhouse. Rumen … materials, rumen microbes and their enzymes are an optimal study subject that could lead to more sustainable energy …
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Micro-Scale Applications Group
… the genetic makeup of natural microbial communities using a variety of cutting-edge approaches.  Our group also seeks out new approaches that utilize microfluidics/microdroplet technology in order to enhance the quality of single-cell …
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How to Submit Sequencing Samples
… the process needed to prepare and ship samples for sequencing by the JGI.  Additionally it includes instructions on … Project Manager or [email protected] . … 1) Review JGI sample QC requirements and protocols Obtaining … sends Project Manager (PM) a list of organism names (or for metagenomes, sample names).  Need help naming your …
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Natural Prodcast Episode 10: A Primer on Genome Mining
DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s … like, and then you could characterize it. The classical study that demonstrated this is Challis et al, Chemistry and … if an order is uncultured (blue; represented only by metagenome-assembled genomes or MAGs) or cultured (gray; …
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Natural Prodcast Episode 14: Nigel Mouncey
… for Episode 14 of Natural Prodcast . There’s been a lot going on, so I took a little break, but I’m hoping that from … And these were not in natural products, these were in studying regulatory mechanisms of, first, E. coli and then … in an obvious way. NIGEL MOUNCEY: We did a little bit of metagenome screening work and did find related clusters. But …
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Products
The JGI has diverse capabilities in: DNA and RNA sequencing, Sample and library preparation, … all products are available for all proposal calls.   Please review the call language carefully to ensure that your … metabolites and unidentified features in spectra. 167/214 Metagenome Metatranscriptome Environmental transcript …
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Frequently Asked Questions: Proposal Submission
Questions about our proposal submission process. You can review successful letters of intent and submissions at the bottom of the page.  … Review the list of open calls ; click on the call link to see specific details including project types …
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