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    Screencap of green algae video for PNAS paper
    Green Algae Reveal One mRNA Encodes Many Proteins
    A team of researchers has found numerous examples of polycistronic expression – in which two or more genes are encoded on a single molecule of mRNA – in two species of green algae.

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    Advances in Rapidly Engineering Non-model Bacteria
    CRAGE is a technique for chassis (or strain)-independent recombinase-assisted genome engineering, allowing scientists to conduct genome-wide screens and explore biosynthetic pathways. Now, CRAGE is being applied to other synthetic biology problems.

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    Maize can produce a cocktail of antibiotics with a handful of enzymes. (Sam Fentress, CC BY-SA 2.0)
    How Maize Makes An Antibiotic Cocktail
    Zealexins are produced in every corn variety and protect maize by fending off fungal and microbial infections using surprisingly few enzymes.

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    Poplar (Populus trichocarpa and P. deltoides) grow in the Advanced Plant Phenotyping Laboratory (APPL) at Oak Ridge National Laboratory in Tennessee. Poplar is an important biofuel feedstock, and Populus trichocarpa is the first tree species to have its genome sequenced — a feat accomplished by JGI. (Image courtesy of Oak Ridge National Laboratory, U.S. Dept. of Energy)
    Podcast: Xiaohan Yang on A Plantiful Future
    Building off plant genomics collaborations between the JGI and Oak Ridge National Laboratory, Xiaohan Yang envisions customizing plants for the benefit of human society.

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    Expansin complex with cell wall in background. (Courtesy of Daniel Cosgrove)
    Synthesizing Microbial Expansins with Unusual Activities
    Expansin proteins from diverse microbes have potential uses in deconstructing lignocellulosic biomass for conversion to renewable biofuels, nanocellulosic fibers, and commodity biochemicals.

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    High oleic pennycress. (Courtesy of Ratan Chopra)
    Pennycress – A Solution for Global Food Security, Renewable Energy and Ecosystem Benefits
    Pennycress (Thlaspi arvense) is under development as a winter annual oilseed bioenergy crop. It could produce up to 3 billion gallons of seed oil annually while reducing soil erosion and fertilizer runoff.

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    Artistic interpretation of CheckV assessing virus genome sequences from environmental samples. (Rendered by Zosia Rostomian​, Berkeley Lab)
    An Automated Tool for Assessing Virus Data Quality
    CheckV can be broadly utilized by the research community to gauge virus data quality and will help researchers to follow best practices and guidelines for providing the minimum amount of information for an uncultivated virus genome.

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    Unicellular algae in the Chlorella genus, magnified 1300x. (Andrei Savitsky)
    A One-Stop Shop for Analyzing Algal Genomes
    The PhycoCosm data portal is an interactive browser that allows algal scientists and enthusiasts to look deep into more than 100 algal genomes, compare them, and visualize supporting experimental data.

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    Artistic interpretation of how microbial genome sequences from the GEM catalog can help fill in gaps of knowledge about the microbes that play key roles in the Earth's microbiomes. (Rendered by Zosia Rostomian​, Berkeley Lab)
    Podcast: A Primer on Genome Mining
    In Natural Prodcast: the basics of genome mining, and how JGI researchers conducted it in IMG/ABC on thousands of metagenome-derived genomes for a Nature Biotechnology paper.

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    Image of Octopus Springs for the CSP annual call
    Letters of Intent are due April 12, 2021 for the annual Community Science Program (CSP) call focused on large-scale genomic science projects that address specific areas of special emphasis and exploit the diversity of JGI capabilities.

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    SIP engagement webinar
    “SIP technologies at EMSL and JGI” Webinar
    The concerted stable isotope-related tools and resources of the JGI and the Environmental Molecular Sciences Laboratory (EMSL) may be requested by applying for the annual “Facilities Integrating Collaborations for User Science” (FICUS) call.

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    CSP Functional Genomics Call Ongoing
    The CSP Functional Genomics call helps users translate genomic information into biological function. Proposals submitted by July 31, 2021 will be part of the next review.

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    Aerial photo of the switchgrass diversity panel late in the 2020 season at the Kellogg Biological Station in Michigan. (Robert Goodwin)
    A Team Effort Toward Targeted Crop Improvements
    A multi-institutional team has produced a high-quality reference sequence of the complex switchgrass genome. Building off this work, researchers at three DOE Bioenergy Research Centers have expanded the network of common gardens and are exploring improvements to switchgrass.

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    Artistic interpretation of how microbial genome sequences from the GEM catalog can help fill in gaps of knowledge about the microbes that play key roles in the Earth's microbiomes. (Rendered by Zosia Rostomian​, Berkeley Lab)
    Uncovering Novel Genomes from Earth’s Microbiomes
    A public repository of 52,515 microbial draft genomes generated from environmental samples around the world, expanding the known diversity of bacteria and archaea by 44%, is now available .

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    Green millet (Setaria viridis) plant collected in the wild. (Courtesy of the Kellogg lab)
    Shattering Expectations: Novel Seed Dispersal Gene Found in Green Millet
    In Nature Biotechnology, a very high quality reference Setaria viridis genome was sequenced, and for the first time in wild populations, a gene related to seed dispersal was identified.

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Our Science
Home › Science Highlights
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August 20, 2010

A bacterium for biohydrogen production

Breaking down organic wastes typically involves microbial communities of bacteria and archaea working in concert with methanogens, which remove the hydrogen generated during the degradation process. The interactions between these syntrophic communities are being studied to understand the roles these microbes play individually and and as whole. In the August 2010 issue of the journal… [Read More]

August 13, 2010

Updating Genomics and Bioinformatics Courses for Undergraduates

Responding to the National Research Council of the National Academies’ call to “involve students in working with real data and tolls that reflect the nature of life sciences research in the 21st century,” the DOE JGI’s Education Program, headed by Cheryl Kerfeld, collaborated with faculty members from several universities around the country to develop bioinformatics… [Read More]

August 5, 2010

Terephthalate-degrading consortia

Terepthalate is the byproduct of a common compound used extensively by the plastics industry. The volume of terephthalate wastewater generated is equivalent to the amount of wastewater generated by 20 million people. Syntrophic communities are composed of bacteria that break down organic matter and methanogens that remove the hydrogen released to ensure the degradation process… [Read More]

July 30, 2010

Tammar wallaby foregut microbiome

Australia and New Zealand were separated from other land masses for millennia, and the unique marsupials found there such as kangaroos and wallabies have forestomachs adapted to efficiently break down lignocellulosic plant mass to extract nutrients. Australian marsupials such as the Tammar wallaby (above) contain unique, uncultured bacteria that could be useful in breaking down… [Read More]

July 23, 2010

Marine Metagenomics Elucidate Role in Global Carbon Cycle

Marine eukaryotes such as diatoms and phytoplankton sequester as much as 50 billion tons or gigatons of carbon annually, but very little is known about the tiny microorganisms that primarily make up this group, and their role in the global carbon cycle. To help answer this question, a team led by DOE JGI collaborator Alexandra… [Read More]

July 16, 2010

S. commune genome makes three biomass-degrading fungi characterized

Many sequencing projects at the DOE JGI focus on identifying enzymes in organisms such as fungi that can break down cellulose in plant mass to help bring down the cost of biofuel production. As DOE JGI Fungal Genomics Program head Igor Grigoriev noted, “When we go into a forest we don’t see layers of dead… [Read More]

July 9, 2010

Volvox genome belies “Small is Simple” Axiom

In the July 9, 2010 issue of Science, researchers led by the DOE JGI and the Salk Institute report on the 138 million-base genome of the multicellular alga Volvox carteri. The work complements the genome of the unicellular alga Chlamydomonas reinhardtii, which was sequenced by the DOE JGI in 2007 and is used by researchers… [Read More]

June 18, 2010

Characterizes/Publishes Anti-Reservoir-Souring Microbe

Scanning electron micrograph of D. acetiphilus strain N2460T. From H. Kiss et al, doi.org/10.4056/sigs.892105Reservoir souring, the production of hydrogen sulfide in oil wells as a result of downhole activity by a specialized group of microorganisms called sulfate-reducing bacteria (SRB), is a detrimental process of great concern to the oil industry. As petroleum reserves age and water injection is implemented for pressure maintenance, there is an inherent risk of… [Read More]
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