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… from uncultivated microbes and viruses. We develop computational approaches to sift through thousands of metagenomes for signatures of viruses and novel microbial … applications. By recovering population genomes from metagenomes, we gain insights into microbial interactions, …

… and their evolution. The Program focuses on developing computational tools and visualization resources that support … in natural environments. Integrating metatranscriptomes and metagenomes can, for instance, deepens our understanding of … knowledge, enabling global exploration. We develop computational tools for analyzing viral fragments via IMG/VR …

… Functional Genomics Methods Click the drop-downs on the left to learn more. …

… growth of DNA sequencing data, coupled with recent computational technology advances in management, processing … functional dark matter as well as the development of novel methods to enable large-scale comparative analysis, mining … Interpretation-a benchmark of metagenomics software. Nature Methods  14(11):1063-1071 Bowers RM, et al. (2017) Minimum …

… changes. With advanced mass spectrometry techniques and computational tools, the program supports foundational … The program employs advanced mass spectrometry-based methods to analyze metabolites from a wide range of … soils. Through a combination of experimental workflows and computational analysis, JGI scientists are able to link …

… microbial lineages through advanced genomic techniques and computational analysis: Through cutting-edge genomic techniques and computational approaches, we work to catalog and understand … Developing rapid and accurate methods for identifying potential biological threats in …

… the Woyke laboratory focuses on the utility of single-cell methods to access genetic material of uncultivated taxa of … genomes are critical to serve as phylogenetic anchors for metagenomes studies.  While uncovering the metabolic … Kintai Therapeutics , Cambridge, MA Jessica Jarett: Computational Biologist, AnimalBiome Asaf Levy: Assistant …

… microbial communities. This involves both experimental and computational exploration of uncultivated viral diversity, … and virus genomes have been assembled and reported from metagenomes, our understanding of the impacts of these … including laboratory incubations and microfluidics methods to better investigate the host range of phages in …

… liquid chromatography mass spectrometry (LC-MS) based methods in combination with advanced computational analysis.   Overview of metabolomics products … A wide range of metabolites are identified using LC-MS/MS methods optimized for specific types of molecules.   …

… transcriptomics barcode-based genetics (RB-TnSeq), and computational genomics to better understand the … with Arabidopsis thaliana. Using a coupled experimental and computational approach, we employ various omics … strain engineering and experimental characterization methods, in addition to bioinformatics tools to elucidate …

… scales ranging from single genes and individual genomes to metagenomes to systems-level modeling and understanding. JGI …

… By integrating cutting-edge technologies and data-driven methods, the program equips researchers worldwide to tackle … using deep-coverage RNA-seq analyzed in a consistant computational framework. It enables cross-species … research to achieve genotype-independent, automated methods, and delivering scalable transformation services …