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… and their evolution. The Program focuses on developing computational tools and visualization resources that support … in natural environments. Integrating metatranscriptomes and metagenomes can, for instance, deepens our understanding of … tools for analyzing viral fragments via IMG/VR and methods to capture  environmental viral populations. …

… growth of DNA sequencing data, coupled with recent computational technology advances in management, processing … functional dark matter as well as the development of novel methods to enable large-scale comparative analysis, mining … Interpretation-a benchmark of metagenomics software. Nature Methods  14(11):1063-1071 Bowers RM, et al. (2017) Minimum …

… changes. With advanced mass spectrometry techniques and computational tools, the program supports foundational … The program employs advanced mass spectrometry-based methods to analyze metabolites from a wide range of … soils. Through a combination of experimental workflows and computational analysis, JGI scientists are able to link …

… from uncultivated microbes and viruses. We develop computational approaches to sift through thousands of metagenomes for signatures of viruses and novel microbial …

… the Woyke laboratory focuses on the utility of single-cell methods to access genetic material of uncultivated taxa of … genomes are critical to serve as phylogenetic anchors for metagenomes studies.  While uncovering the metabolic … Kintai Therapeutics , Cambridge, MA Jessica Jarett: Computational Biologist, AnimalBiome Asaf Levy: Assistant …

… liquid chromatography mass spectrometry (LC-MS) based methods in combination with advanced computational analysis.   Overview of metabolomics products … A wide range of metabolites are identified using LC-MS/MS methods optimized for specific types of molecules.   … Find …

… transcriptomics barcode-based genetics (RB-TnSeq), and computational genomics to better understand the … with Arabidopsis thaliana. Using a coupled experimental and computational approach, we employ various omics … strain engineering and experimental characterization methods, in addition to bioinformatics tools to elucidate …

Developing forward-looking strategies for the deployment of computational workflows at peta- and exa- scales on … specificity of single cells and genomes extracted from metagenomes, and also as a metric for quality control within … datasets. IMG is a collaboration between the JGI and the Computational Biosciences Group at the Computing Sciences …

… microbial communities. This involves both experimental and computational exploration of uncultivated viral diversity, … overview and major challenges of host prediction methods for uncultivated phages.  Current Opinion in …

… scales ranging from single genes and individual genomes to metagenomes to systems-level modeling and understanding. JGI …

… developments in microbial genomics, metagenomics, and computational biology, and to empower them with the … 230,000 metagenome-assembled genomes (MAGs), and 40,000+ metagenomes along with curated environmental- and other … no dedicated compute infrastructure is required to perform computational analysis. IMG/M user interface is designed for …

… enabling ever-higher levels of throughput. We also develop methods for efficient QA/QC based on next-generation … group: The applications group is focus on developing methods for converting digital information from sequence …