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… Team develops a computational pipeline to sift and characterize RNA virus sequences.  A zoo once … contain the RdRP sequence. The work resulted from a three-way collaboration that began in 2019, recalled Uri Neri of … The U.S. Department of Energy Joint Genome Institute, a DOE Office of …

… Our research is focused on the discovery and characterization of … data. We use multi-omics (metagenomics, metatranscriptomics, single cell genomics and phylogenomics) and machine … Tree of Life. We then investigate the coding potential to find novel functions that may impact microbiome structure …

… Find protocols provided by JGI and the JGI user community … preparation tools, high molecular-weight DNA extraction and RNA preparation.  JGI sample QC protocols can be found here … Tips for High Molecular Weight DNA extraction: … RNA Extraction Protocols: … iTag protocols: …

… Below is a brief description of the process needed to prepare and ship samples for sequencing by the JGI.  Additionally it includes instructions on … 1) Review JGI sample QC requirements and protocols Obtaining DNA and RNA of suitable quantity and … 1) Complete Sample Metadata form Sample metadata is collected via …

… Microbes drive critical ecosystem functions and affect global nutrient cycling, … however they do so under strong constraints exerted by viruses. Research in the viral genomics group aims at … and host cell take-over by viruses, and attempts to evaluate ecosystem-level impacts of viral infections. The …

… DAN: Welcome back for episode 9 of Natural Prodcast. This … of which natural products chemistry is one. DAN: So, I’ve always known Roger as an expert in natural product structure … elucidation and genome mining, and how we might start to better connect those two things, because I think that’s …

… DAN UDWARY: You’re listening to the Department of Energy … that are natural to this complex, then we might have a better understanding of what is what. This is not new. It … will say that a siderophore is a secondary metabolite. In a way, that doesn’t tell you nothing. It’s not very useful to …

… DAN: You’re listening to the US Department of Energy Joint … expensive process. And so, drug companies really needed ways to kind of short-circuit that, and natural products … how these systems evolve. ALISON: And we want to be able to better understand how these particular secondary metabolites …

… DAN: You’re listening to the US Department of Energy Joint … me a lot, though I actually edited most of that out. But anyway, here’s our conversation with one of my favorite human … are going to happen, that become toxic, and be able to better, perhaps, inform the public when a toxic event is …

… The JGI’s Microbial Program focuses on using cutting-edge sequencing, annotation and analysis techniques to explore the vast and diverse world of microbes. Studying … The Microbial Program focuses on using advanced sequencing technologies to explore microbial diversity — with an emphasis on …

… DAN: You’re listening to the US. .Department of Energy Joint … DAN: We know each other pretty well. So I feel like it’s always fun to talk to you. I’m particularly interested… Well, … interesting – when you can begin to see these guys building better weapons against one another. That gives us …

… DAN: You’re listening to the US Department of Energy Joint … are definitely an expert in natural products. And I’ve always known you as “the enediyne guy”. And so enediynes are … JGI to try to find new enediyne clusters and to figure out better ways to produce them. Do you want to talk a little …