Previous collaborations between the University of Washington team and the DOE JGI involving both single genome and metagenomic sequencing have greatly enhanced the community’s ability to explore the diversity of bacteria functionally active in metabolism of single carbon compounds, known as methylotrophs, isolated from Lake Washington (Seattle, Washington) sediment. Sequencing genomes of 50 methylotroph isolates from the Lake Washington will further enhance the methylotroph community knowledge database providing a much higher level of resolution of global (meta)transcriptomic and (meta)proteomic analyses, as well as species interaction studies, informing a better understanding of biogeochemical cycling of carbon and nitrogen.
Principal Investigators: Ludmila Chistoserdova, University of Washington
Program: CSP 2011