Search

… of novel bacterial, archaeal and eukaryotic microbes and viruses in environmental sequence data. We use multi-omics (metagenomics, … investigate the coding potential to find novel functions that may impact microbiome structure and biogeochemical …

… there are any kind of dated references to the news, that’s why. But it was a really fun conversation. And I think … it would work, but we actually found fosmids. And we sequenced the whole fosmid at the time with Sanger … even in primary metabolism or in certain snips of viruses or something. I don’t know. Then I think making sure …

… however they do so under strong constraints exerted by viruses. Research in the viral genomics group aims at … in virus:host interaction and host cell take-over by viruses, and attempts to evaluate ecosystem-level impacts of viral infections. The Viral Genomics Group is hosted within the …

When submitting sequences to the JGI DNA Synthesis program, please include the following items: … Sequence files for all constructs should be emailed to  … several easy-to-use open source tools for converting DNA sequence files into well-formed GenBank files. ApE is an …

… working on harder organisms, with the kinds of challenges that usually lead to surprises and really great discoveries! … you maybe explain what’s going on with their biology and why they’re so important to natural products? ERIC:  Sure. … turns a peptide, for example, from a disordered sequence into an antibiotic that kills bacteria through a …

Plants are complex organisms that harbor a fantastic diversity of cell types and … symbionts, detrimental microbial pathogens, and associated viruses that all contribute to a dynamic ecosystem. We are … have recently identified resident bacteriophages (viruses infecting bacteria) in the plant growth-promoting …

… archaea, and micro-eukaryoes, along with their associated viruses and mobile genetic elements. Beyond exploring and … the Program aims to unlock the fundamental principles that govern ecosystem processes. This research provides … comprising the largest public collection of plasmid sequences identified from genomes, SAGs, MAGs, metagenomes …

… from the Chemistry department at the University of Utah, so that makes him one of Jackie’s colleagues. Aaron is doing … of their synthases so that we can start to use the DNA sequence to predict or just understand better the language … your interest in getting into natural products. DAN: Why are you here at SIMB? AARON PURI: Yeah. Thanks Jackie. …

Berkeley National Laboratory. Being a User Facility means that scientists from all over the world bring us big … stories about natural products, so you can get a feel for why I think they’re so important, and we’ll start to explain … this happened have a tendency to be susceptible to a fungal infection of rye grain – a specific fungus, Claviceps …

And we talk a lot about some of the technical challenges to that, most of which seem to be history.   I should mention … out introns and dealing with, you know, weirdness in the sequence. You know, some clusters are not clustered…   … it so easily with fungi. So…   NANCY: Yeah, I don’t know why. For example, with that – actually there’s a good talk …

Usually when we do these interviews, most of the people that I think we’ve talked to so far I either know … culture-disconnected. Like we’ll take some soil samples and sequence all the bugs out of that or whatever. And so I was … methicillin-resistant Staphylococcus aureus . Can you share why finding treatments for these microbes is so important? …