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… by exploring plants’ role in capturing carbon, detoxifying soils, interacting with other organisms, and adapting to … facing humanity. A major focus are biofuel feedstock species and plant-microbe interactions, advancing efforts to … the globe to identify genes to improve our domesticated species.  The program supports the development of …

… through end-to-end automation — and further advancing sequence applications, single cell genomics, biodesign, and … [QA/QC]), large-scale liquid handling automation, and sequence analysis. … access to cutting-edge cell sorting, DNA amplification, and sequence analysis to recover the genomes of uncultivated …

… When submitting sequences to the JGI DNA Synthesis program, please include … Sequence files for all constructs should be emailed to  … several easy-to-use open source tools for converting DNA sequence files into well-formed GenBank files. ApE is an …

… approaches to identify and characterize genomic information from uncultivated microbes and viruses. We develop … Our research focuses on the assembly of metagenomic sequence data into microbial genomes, which is of … potential applications. By recovering population genomes from metagenomes, we gain insights into microbial …

… there are any kind of dated references to the news, that’s why. But it was a really fun conversation. And I think … we’re thinking they’re obligate marine. There’s so far no species or no strains known that really grow in freshwater. … it would work, but we actually found fosmids. And we sequenced the whole fosmid at the time with Sanger …

… the paradigm of how to discover natural products. So, why I’m very excited to be working with Dan, you, with the … develop enabling technologies. ie how to translate the ATGC sequence into discrete small molecules. So, Dan, I’m very … Fleming – the discovery of penicillin from the fungal species – probably told us that fungi could be very …

… does some really exciting work there. And I thought, well, why don’t we try to go to Alaska and see what we can find … able to produce chemistry that deals with reactive oxygen species and so potentially could go down that route.  DAN: … with any kind of gene cluster identification, doing it with sequence alone you have to have some kind of a template to …

… shown today is it's more a quorum sensing within a single species. DAN: Within a species. Genus? BETSY PARKINSON: So … The genes are pretty much 100% identical. We don't know why one is expressed over the other. As far as whether we're … usually serve as dimers, and then they will bind to certain sequences of DNA. And when they bind to those certain …

… and eukaryotic microbes and viruses in environmental sequence data. We use multi-omics (metagenomics, … to adapt to live in Earth's most extreme environments, from deep-sea oceanic fluids to hypersaline lakes and … Leveraging artificial intelligence to extract insights from large-scale biological datasets: Our group develops and …

… conversation with Aaron Puri. He is an Assistant Professor from the Chemistry department at the University of Utah, so … of their synthases so that we can start to use the DNA sequence to predict or just understand better the language … your interest in getting into natural products. DAN: Why are you here at SIMB? AARON PURI: Yeah. Thanks Jackie. …

… the product and deliverables as well as target cycle times from sample receipt to completion of standard analysis.  Raw … sequencing products below. In addition, JGI will submit raw sequence data to  SRA at NCBI once the standard analysis is … in length, cloned into vector of choice Glycerol stock of sequence verified clone 102/NA DNA Synthesis Constructs …

… through analyzing and harnessing genomic information from plants, fungi, algae, non-medical microbes, microbial … in doing so enabled the JGI to be the first to publish the sequence analysis of the target chromosomes 5, 16, and 19, … to advance basic science by sequencing scores of microbial species as well as several model organisms and contributing …