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DOE Metrics
FY 2025 DOE Metrics Sequencing Quarter Total Bases (Trillions) …     2,167     *Includes Illumina and PacBio sequencing platforms. **Operating Hours target is based on 98% of the total … 2,208 102% *Includes Illumina and PacBio sequencing platforms. **Operating Hours target is based on 98% of the total …
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Viruses Reprogram Cells into Different Virocells
Microbial cells infected by viruses undergo metabolic reprogramming. …
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Single Cell Research Group
… of interest. One such effort is targeted at environmental cells that are from candidate phyla, major branches in the … begin filling this gap. A primary goal is to get  insights into the coding potential of candidate phyla  to decipher … Jensen G. J., Kyrpides N. C., Koonin E. V., Woyke T . Giant viruses with an expanded complement of translation system …
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Natural Prodcast Episode 7: Ben Shen
… for every episode we put out. I actually put a lot of time into preparing those transcripts, so I hope somebody’s going … of electrons that becomes really reactive. And so, different types of enediyne molecules can bind to different … is always associated with toxicity, basically, killing cells. ALISON: Right, because they’re so reactive. BEN: …
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Institutional User Agreements
Every approved proposal starts with a User Agreement — before any work can begin, including the submission of samples for sequencing, or the submission of sequencing data for synthesis. This agreement, required by the DOE for all work performed in its User Facilities, is a …
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Micro-Scale Applications Group
… of single-cell genomes and directly link functional information with individual cells. Research Team    … The JGI uniquely offers the first … (BONCAT+FACS). To provide additional functional insights into microbial genomes, the JGI now uses laser …
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Natural Prodcast Episode 18: A CSP Primer
… idea that fits within our mission, we’re happy to help you figure out if it’s a good fit. Everyone we talked to said … bit confusion about what a CSP is as opposed to other different kinds of federal grants like through NIH or NSF … genomes. Fungal plant, algal genomes, a lot of effort goes into generating these data sets. There’s a lot of manual …
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Viral Genomics Group
… however they do so under strong constraints exerted by viruses. Research in the viral genomics group aims at … in virus:host interaction and host cell take-over by viruses, and attempts to evaluate ecosystem-level impacts of … overview and major challenges of host prediction methods for uncultivated phages.  Current Opinion in Virology .  49 …
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Natural Prodcast Episode 1: The Primer, Part 1
Secondary Metabolites Science Program, which I was hired into, and my job is to do cool research, and also to talk to … they figured out that they could culture the plant cells and produce enough that way in really large like 7500 … experience some natural products now but maybe that’ll be a different episode. I mean, I’m sure we are experiencing some …
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New Lineages of Life Group
… of novel bacterial, archaeal and eukaryotic microbes and viruses in environmental sequence data. We use multi-omics … 5 (3) Schulz et al. (2018) Hidden diversity of soil giant viruses. Nature Communications. 9 (1), 1-9 Schulz et al. … The ISME Journal. 8 (8), 1634-1644 … Publications … For further details, please reach out to the Group Lead …
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Plant-Microbial Interactions Group
… symbionts, detrimental microbial pathogens, and associated viruses that all contribute to a dynamic ecosystem. We are … experimental characterization methods, in addition to bioinformatics tools to elucidate phage function in this … We are using these methods to understand how plant cells respond to low nutrient conditions (low nitrogen or …
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Natural Prodcast Episode 22: Alison Narayan
… super fun to hear about what folks are up to in a slightly different niche in chemical enzymology. So, we talked about … in synthetic chemistry as were you and then made their way into the field of natural products in some way, shape, or … make that association. DAN UDWARY: So I guess what is the conceptual difference between a biocatalyst and an enzyme? …
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