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Sequencing Technologies & Products
… through end-to-end automation — and further advancing sequence applications, single cell genomics, DNA synthesis, … [QA/QC]), large-scale liquid handling automation, and sequence analysis. … uniquely offers quantitative Stable Isotope Probing (SIP) Metagenomics to the broader scientific community. The …
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Metagenome Program
… such as quantitative stable isotope probing (qSIP)-metagenomics and metatranscriptomics, to metagenomics and metabolomics data, shedding light on … unexpected microbial clades. We leverage  genome-resolved metagenomics and targeted gene searches to expand … data science by enabling comparative genomics and metagenomics analysis through the IMG/M platform. Further, …
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Environmental Genomics Group
… Our research focuses on the assembly of metagenomic sequence data into microbial genomes, which is of … from labeled nutrients into biomass. When paired with metagenomics, qSIP can decipher active microbial functions … Profile HMM search across all IMG metagenomes, capturing sequence diversity for proteins of interest. …
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Natural Prodcast Episode 24: Jackie Winter and SMC
… about microbiology and natural products from the Great Salt Lake, and you’re going to learn, like me, what a “haboob” … is like, what’s your origin story in natural products? Why are you doing this? JACLYN WINTER: I’ll kind of go back … have an E. coli strain that we’ve been working on that we sequenced the genome. And it has 17 resistant genes on a …
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New Lineages of Life Group
… and eukaryotic microbes and viruses in environmental sequence data. We use multi-omics (metagenomics, metatranscriptomics, single cell genomics and … environments, from deep-sea oceanic fluids to hypersaline lakes and hyperthermal springs. This research provides …
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Natural Prodcast Episode 12: Nadine Ziemert
… there are any kind of dated references to the news, that’s why. But it was a really fun conversation. And I think … it would work, but we actually found fosmids. And we sequenced the whole fosmid at the time with Sanger … soil. But we also have, in collaboration with other people, lake sediments. We have microbiomes from different …
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Sequencing Submission Requirements for DNA Synthesis
… When submitting sequences to the JGI DNA Synthesis program, please include … Sequence files for all constructs should be emailed to  … several easy-to-use open source tools for converting DNA sequence files into well-formed GenBank files. ApE is an …
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Microbial Program
… addressing key environmental challenges, such as improving soil health, carbon sequestration and bioeconomy … resequencing, RNA sequencing and epigenomics. Expansion of sequence space:  The JGI generates reference genomes from … of microbial communities based on their metagenome sequence, in the context of reference isolate genomes …
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Metabolomics
… they grow, as well as different types of environments (e.g. soil, lake).  A wide range of metabolites are identified using …
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Special Initiatives & Programs
… capabilities and products . A minimum request of 1 Tb of sequence data is required to qualify for BERSS. For DNA … from lignin left over after biomass processing. Great Lakes Bioenergy Research Center , led by the University of … and personnel resources for genomic research and sequence-based science.  Projects include de novo generation …
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Natural Prodcast Episode 11: Marnix Medema
… about the basics of genome mining, which is using DNA sequence to identify and interpret biosynthetic, secondary … biological perspective, like what was this bacterium, and why did your group want to study it? Marnix Medema: You mean … the action of the microbiome because if you sterilize the soil, the protective effect is gone. You can transplant the …
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Natural Prodcast Episode 23: Aaron Puri
… of their synthases so that we can start to use the DNA sequence to predict or just understand better the language … your interest in getting into natural products. DAN: Why are you here at SIMB? AARON PURI: Yeah. Thanks Jackie. … put into antiSMASH after downloading it was isolated from Lake Washington. So it’s really interesting that it was …
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