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… to explore the vast and diverse world of microbes. Studying bacteria and archaea, including those associated with … of underexplored bacterial and archaeal lineages that are important for bioeconomy applications. By expanding our … resequencing, RNA sequencing and epigenomics. Expansion of sequence space:  The JGI generates reference genomes from …

When submitting sequences to the JGI DNA Synthesis program, please include the following items: … Sequence files for all constructs should be emailed to  … several easy-to-use open source tools for converting DNA sequence files into well-formed GenBank files. ApE is an …

… you maybe explain what’s going on with their biology and why they’re so important to natural products? ERIC:  Sure. So sponges are … turns a peptide, for example, from a disordered sequence into an antibiotic that kills bacteria through a …

… there are any kind of dated references to the news, that’s why. But it was a really fun conversation. And I think … it would work, but we actually found fosmids. And we sequenced the whole fosmid at the time with Sanger … environments, varied with a lot of metadata. I think that’s important. Really, also, having the same protocols– I think, …

… focuses on the exploration of secondary metabolites across bacteria, fungi, algae and plants. These molecules, which … computational analyses of BGC size and complexity, BGC sequence composition, metabolic similarity & compatibility, … metabolism research, “Natural Prodcast” serves as an important line of communication to the scientific community. …

… learned a lot so much history from this conversation about why the ocean was basically unexplored until the 70s, and … other countries. And it became quite clear that this was an important field evolving, not only through me, but as other … forward to seeing the data when it finally gets off the sequencers. The pandemic has obviously slowed JGI down a …

… cell types and associated organisms, including fungal and bacterial symbionts, detrimental microbial pathogens, and … This is a dynamic and complex ecosystem that includes bacteria, fungi, viruses. Resident viruses can be found in a myriad of bacterial strains, whereby they can modulate host …

… least, talk to us, first about my definitions of things and why I am wrong, and also talk about some of the great … be using for what we do are, and why there and why it’s important to make those distinctions. FRANCISCO … to approach it is more related to what JGI does, which is sequence genomes. And we just published last year in the …

… on the chemistry. There’s so much work to be done. And more importantly, what we know is they’re quite selective in some … does some really exciting work there. And I thought, well, why don’t we try to go to Alaska and see what we can find … with any kind of gene cluster identification, doing it with sequence alone you have to have some kind of a template to …

… pipelines.  You will receive automated emails as raw sequence data becomes available, and as analysis is …

… at JGI start with sequencing, but where else did those sequences go? Like, what are the other scientific tools we … a good fit for working with the JGI? TANJA WOYKE: The very important first criteria– DAN UDWARY: So here’s what we … that describe the work. In general. Scientific merit and why it’s important. The DOE mission is one of these …