Results
… collaborative user projects, the JGI’s Plant Program delves into the natural world’s potential to address global challenges by exploring plants’ role in capturing carbon, detoxifying soils, … to regulate Earth's carbon balance, to exploring the genetic basis of how plants have naturally adapted to varied …
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… Plants are complex organisms that harbor a fantastic diversity of cell types and associated organisms, including fungal and bacterial symbionts, detrimental … single-cell and spatial transcriptomics barcode-based genetics (RB-TnSeq), and computational genomics to better …
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… Program works to uncover the roles of small molecules in biological systems, linking them with genomic data to … metabolomics fuels the discovery of novel metabolites, genes, and proteins. It also enables exploration of energy … biogeochemical processes, development of high performance plants and microbes, and understanding microbiome …
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… Synthesis Program supports a wide range of projects, from single-gene synthesis to the synthesis of entire chromosomes, … program enables the design and synthesis of complex genetic pathways and biosystems. It The program fosters … in advancing functional genomics, focusing on developing genetic systems that can address global energy and …
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… The JGI has diverse capabilities in: DNA and RNA sequencing, Sample and library preparation, Biodesign and pathway engineering Mass spectrometry based metabolomics Below is a … DNA Synthesis Constructs <5kb in size Single gene or multiple small genes assembled to less than 5kb in length, …
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… It was unpublished at that point. But people would push out gene clusters maybe once a month at most. Maybe twice a … we built this as a platform that allows us for– it’s geared toward mammalian systems. But it allows us to assay on a … the metabolome into well plates. And we can use our fancy multiplexed activity metabolomics method to tell us what’s …
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… my undergraduate in microbiology and then PhD in microbial genetics in the UK. And came across to the US for a couple … me really interested in microbial gene regulation and some pathways. And I thought I’d take an academic job then, but I … products projects that we had in my group which was bioengineering bio-process R&D, BBRD, a group of about 75 …
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… of secondary metabolites across bacteria, fungi, algae and plants. These molecules, which are not essential for … growth, provide critical advantages to the organisms producing them, and are often involved in defense, nutrient acquisition and communication. … conditions, with only a small portion of the biosynthetic gene clusters (BGCs) being expressed. The program works to …
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… The focus of this group, in recent years, has been to bring generalizable … to bacteria, yeasts and algae previously with little to no genetic tools enabling heterologous expression and …
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… into functional assessments. This is done by synthesizing genes, pathways, and whole chromosomes for bioenergy, nutrient … user project design, assembly, and quality control Strain Engineering Group : a research & development group and … sequence design for assembly by Gibson, Yeast recombination and Golden Gate methods …
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… See below for examples of successful Letters of Intent to our Community Science Program Large-Scale Call, as well as successful submissions to our CSP New Investigator, CSP Functional Genomics, and Facilities Integrating Collaborations for User Science calls. These …
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… bioprospecting vs biopiracy, early stage drug discovery in general, and a possible data-driven future for plant natural … that they make? CASSANDRA QUAVE: Yeah, so I mean my path towards natural products and medical ethnobotany really … compound is not the answer. Some cases, it’s actually multiple compounds acting in synergy which is scientifically …
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