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A genetic architecture that is characteristic of the sex chromosomes of mammals is, for the first time, … and female gametes in one individual. But some, including shrub willow  Salix purpurea , employ the evolutionary … been sequenced with sufficient resolution to analyze their structure. Scientists found both a gene likely important for …

… here today, and we wanted to talk to her about a whole list of things. So we have a Scripps background shared together, … of natural products from invertebrates, mostly. Dan Udwary: Structure elucidation, yeah. Kate Duncan: Right, yeah, so … really cool and really exciting. But what’s sometimes surprising for people is, like I said at the beginning, even …

… (Trillions) Operating Hours Goal Actual Total* Actual % of Goal Goal (hours)** Actual Total Actual % Goal FY 2025 … Actual Total Actual % Goal FY 2024 Total 650.0 870.574 134% 8,784 8,688 101.2% Q1 2024 162.5 197.381 121% 2,164 … that sequencing machines are available to produce data. FY 2010 Summary Quarter Total Bases (Billions) Total Bases …

… … DAN: Welcome back for episode 9 of Natural Prodcast. This week, Alison and I talk to Roger … So, I’ve always known Roger as an expert in natural product structure elucidation, but more recently, he’s been leading … is in data analysis strategies. So we’ve seen in the last 15 years, enormous advancements in hardware, both on the NMR …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … a class of natural product with a really cool chemical structure. We try to explain it, but it’s chemistry, so I … contains organisms collected from 40, 50 all the way to the 2010s, so spans more than seven decades. And think about …

… research is focused on the discovery and characterization of novel bacterial, archaeal and eukaryotic microbes and … to find novel functions that may impact microbiome structure and biogeochemical cycles. Research Team    … A … ancient features. Environmental Microbiology. 18 (8), 2326-2342 Schulz and Horn (2015) Intranuclear bacteria: inside the …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … they’re complex, they have different tissues, different structures, different spores. I like looking at that I’m a … tissue-specific in fungi. Some might go be produced in a sexual spore, some might be in an asexual spore, some might …

… for you here today. We got the opportunity to talk to one of the real legends of natural products, Professor Bill … you’re trying to dive and that sort of thing. So it’s not unsurprising this took a while for things to happen. You know, … everybody else started looking at things and doing chemical structures, learning a little bit about things. And that was …

… … DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast, a … So he could see really into this– so he could look into the structure, really seeing that. And I’m always just looking … in the early 2000s? Late 2000s? NADINE ZIEMERT: No, yeah, 2010. ALISON TAKEMURA: 2010, OK. You’re a young faculty. …

The JGI’s DNA Synthesis Program supports a wide range of projects, from single-gene synthesis to the synthesis of entire chromosomes, advancing the development of biofuels, …

… and other omics technologies.  The exponential growth of DNA sequencing data, coupled with recent computational … Science  356: 82-85 Ovchinnikov S. et al. (2017) Protein structure determination using metagenome sequence data. … al. (2014) Stop Codon Reassignments in the Wild. Science 344(6186):909-13 … Research Efforts … Selected Publications …

A nuanced understanding of peat moss drives insight into carbon storage   The … up heavily of sphagnum mosses.  New research identifies sex chromosomes in the plant and illuminates the significant …