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… The JGI’s Microbial Program focuses on using cutting-edge sequencing, annotation and analysis techniques to explore the vast and diverse world of … provides high-quality, large-scale genomic data to advance microbial research that drives sustainable solutions in …

… is focused on the discovery and characterization of novel bacterial, archaeal and eukaryotic microbes and … use multi-omics (metagenomics, metatranscriptomics, single cell genomics and phylogenomics) and machine learning to … of Life. We then investigate the coding potential to find novel functions that may impact microbiome structure and …

… in the Woyke laboratory focuses on the utility of single-cell methods to access genetic material of uncultivated taxa … of interest. One such effort is targeted at environmental cells that are from candidate phyla, major branches in the … in 1985, which highlights our skewed understanding of microbial metabolism towards a minority of cultivated …

… going with us that we want to talk a little bit about. It’s sort of early stages. But I think that is emblematic of some … months of salary and a lousy job with no future. And let’s see what you can do. So with that nine months of salary, I … it too had something unusual that we began thinking about developing. And the company, Nereus, of course, which we …

… genetic elements. Beyond exploring and characterizing microbial diversity, work in the Metagenome Program uses several experimental approaches to assess microbial activity across ecosystems.  By studying microbial … ecosystems and their evolution. The Program focuses on developing computational tools and visualization resources …

… — and further advancing sequence applications, single cell genomics, DNA synthesis, and metabolomics … standards to accurately measure environmental microbiome activity levels. Learn more about SIP metagenomics through … The JGI provides users access to cutting-edge cell sorting, DNA amplification, and sequence analysis to recover …

… Applications group explores the genetic makeup of natural microbial communities using a variety of cutting-edge approaches.  Our group also seeks out new approaches that utilize … technology in order to enhance the quality of single-cell genomes and directly link functional information with …

… thousands of metagenomes for signatures of viruses and novel microbial lineages, and reconstruct metabolic properties … within those genomes. Our aim is to more fully capture microbial and viral diversity, leading to a better … monitoring, bioremediation, and the discovery of novel enzymes and bioactive compounds. …

… types) (Nature Communications 2017, Science 2018, Molecular Cell 2019) and massive reconstruction of genomes from … of the functional dark matter as well as the development of novel methods to enable large-scale comparative analysis, … Analyses of Human Microbiomes Reveal Thousands of Small, Novel Genes. Cell 178(5):1245-1259 Nayfach S, et al, (2019) …

… vision for secondary metabolism, his past in industry in developing natural products for agriculture, and his … because my kids have no interest as far as I can tell. They see me every once in a while grow some plates in– [LAUGHTER] … of countries that we were selling products into, the sort of extended range of applications into companion animal …

… the rest of a natural product molecule around that. That’s sort of a semi-stable configuration of electrons that … its potential application in human medicine. And so, we are developing enabling technology, not only to facilitate the … produced. So I think that I’m excited for everything that seems like, you know, falling into the right place. DAN: …

… are complex organisms that harbor a fantastic diversity of cell types and associated organisms, including fungal and bacterial symbionts, detrimental microbial pathogens, and associated viruses that all … how plants self-organize, influence, and are influenced by microbial partners. We use a variety of genomics-powered …