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The Metagenome Program uses advanced sequencing technologies to decode the genomes of microbes in their … to assess microbial activity across ecosystems.  By studying microbial communities and their interactions, the …

… to explore the vast and diverse world of microbes. Studying bacteria and archaea, including those associated … addressing key environmental challenges, such as improving soil health, carbon sequestration and bioeconomy … capability of microbial communities based on their metagenome sequence, in the context of reference isolate …

ALISON TAKEMURA: So Nadine, what got you interested in studying natural products? NADINE ZIEMERT: Like almost … that easily can identify secondary metabolite pathways in metagenomes, which is still hard to do. We are mining a lot … of these environments? NADINE ZIEMERT: So we started with soil. But we also have, in collaboration with other people, …

… by exploring plants’ role in capturing carbon, detoxifying soils, interacting with other organisms, and adapting to … supports the development of next-generation biofuels by studying perennial grasses and fast-growing trees as … It is now available for both eukaryotic and microbial metagenome assemblies. It is also available as an app in …

Program works to uncover the roles of small molecules in biological systems, linking them with genomic data to … the program supports foundational research related to soil nutrient cycling and health, terrestrial biogeochemical … health, and bioenergy development. … EcoFABs:  For studying microbe-host (or plant-microbiome) interactions …

The IMG group owns and maintains integral components of JGI’s production workflow, … specificity of single cells and genomes extracted from metagenomes, and also as a metric for quality control within … resource for analysis and annotation of genome and metagenome datasets in a comprehensive comparative context. …

… the genetic makeup of natural microbial communities using a variety of cutting-edge approaches.  Our group also seeks out new … that utilize microfluidics/microdroplet technology in order to enhance the quality of single-cell genomes and …

… back to a new session of Natural Prodcast. I’ve got two things I wanted to tell you about in this introduction. First … off through these areas. And you can do– with a teaspoon of soil from outside, you maybe have to do a 10,000-fold … just now switching from intermicrobial interactions, studying intermicrobial interactions by imaging interactions …

… for Episode 14 of Natural Prodcast . There’s been a lot going on, so I took a little break, but I’m hoping that from … And these were not in natural products, these were in studying regulatory mechanisms of, first, E. coli and then … in an obvious way. NIGEL MOUNCEY: We did a little bit of metagenome screening work and did find related clusters. But …

… of natural products, Professor Bill Fenical from Scripps Institution of Oceanography in San Diego. Bill is a pioneer … kept looking for open jobs that said, we want a chemist to study the ocean. And I didn’t find a single job … are many others, including Streptomycetes, which are common soil bacteria. DAN UDWARY: Yeah, we talk about them a lot …

… is Professor Cassandra Quave from Emory University, with joint appointments in the School of Medicine and College of … And for the audience, ethnobotany is the scientific study of the ways that people interact with plants, whether … and culture-disconnected. Like we’ll take some soil samples and sequence all the bugs out of that or …

… of Natural Prodcast. This week, Alison and I talk to Roger Linington, from Simon Fraser University in British Columbia, … the first place? ROGER:  So I was originally trained in the UK, I did my undergraduate degree at University of Leeds. … natural products science as a field, we have arguably been studying microbial natural products in an ordered way for …