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… — and further advancing sequence applications, single cell genomics, biodesign, and metabolomics capabilities.    … factor binding sites across entire genomes. This technology has been further scaled to a multiplexed DAP-seq … The JGI provides users access to cutting-edge cell sorting, DNA amplification, and sequence analysis to …

… to provide direct biochemical datasets to improve our understanding of microbial metabolism. Of particular interest is understanding the distributed and dynamic metabolite …

… in the Woyke laboratory focuses on the utility of single-cell methods to access genetic material of uncultivated taxa … of interest. One such effort is targeted at environmental cells that are from candidate phyla, major branches in the … by Stanley and Konopa in 1985, which highlights our skewed understanding of microbial metabolism towards a minority of …

… is found in nearly all types of bacteria and interacts with cell signaling networks that control many basic cellular … colonization, which can affect pathogenic and symbiotic bacterial interactions with animals and plants, or cause … them useful in a wider range of environments. This new technology enables researchers to directly measure cyclic …

… is focused on the discovery and characterization of novel bacterial, archaeal and eukaryotic microbes and viruses in … use multi-omics (metagenomics, metatranscriptomics, single cell genomics and phylogenomics) and machine learning to … the fascinating world of giant viruses, which challenge our understanding of viral complexity and evolution Our research …

… are complex organisms that harbor a fantastic diversity of cell types and associated organisms, including fungal and bacterial symbionts, detrimental microbial pathogens, and … tools to study this complexity, including single-cell and spatial transcriptomics barcode-based genetics …

… about several different pieces of her work, including bacterial quorum sensing and its effects on regulation of … what DAP-seq is. [Note: Check out this JGI story on DAP-Seq technology.] BETSY PARKINSON: OK. DNA affinity purification … can do these small rings, and so I think we need a better understanding of that. We have a crystal structure, and …

… group to work on sequencing, synthesis and genome mining technology to help access complicated natural product gene … he has an accent, and, so, I don’t really have any trouble understanding him, but I know from the download stats that … is called “development”. So discovery is you find all the innovative leads, and then development is taking the lead …

… those associated with microeukaryotes, enhances our understanding of terrestrial biogeochemical cycling and … laboratory isolation and genome sequencing of underexplored bacterial and archaeal lineages that are important for … in sustainable agriculture, carbon sequestration and biotechnology. …

… the viral genomics group aims at improving our collective understanding of ecological and evolutionary parameters … mechanisms involved in virus:host interaction and host cell take-over by viruses, and attempts to evaluate … have been assembled and reported from metagenomes, our understanding of the impacts of these viruses on microbiome …

… metabolomics enables functional genome annotation, improves understanding of the role small molecules play in diverse …

… brings some new approach or some new way of thinking or technology, that’s usually very beneficial to the field. … cluster with me because it turns out that oftentimes in bacterial genomes if you have a quorum sensing system or the … for the project. DAN: Do you see broader applications for understanding these systems? AARON PURI: Yeah. Are you …