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Extracting the Secrets of Secondary Metabolites
… describe the functions of the biosynthetic gene clusters that produce them. The Impact Secondary metabolites are … secondary metabolites can be complicated because the BGCs that produce them cannot be activated in lab environments. … luminescens proves fatal to insects. It is carried by an infectious nematode and releases toxins into the insect’s …
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Cultivating Symbiotic Antarctic Microbes
… and ‘omics techniques to experimentally determine that Nanohaloarchaeota are symbionts, rather than … in understanding the genomic basis and ecological consequences of microbe-microbe interactions. Using metagenomes … native microbes. Metagenomes from enrichment cultures were sequenced and assembled by the JGI. From these assemblies, …
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PhycoCosm Tutorial
… more about PhycoCosm, the largest interactive collection of sequenced algal genomes, omics data and comparative analysis …
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The Expanding Universe of Methane Metabolisms in Archaea
… as well as tools for analysis. “There is evidence that methanogenesis is one of the oldest metabolisms, with … metabolisms. They also identified a set of 38 marker genes that serve as a core set of genes present in archaea with … et al. study described above, and also led a separate study that is published in the same issue of Nature Microbiology . …
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Introducing New Members of the JGI User Executive Committee
… providing input and advice on JGI policies and practices that affect users and their access to technical capabilities …
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How Filamentous Fungi Sense Food
… a wide array of plant cell-wall degrading enzymes (PCWDEs) that allow them to efficiently break down the wide array of … are like handymen who show up at a job site for a task that requires a flathead screwdriver with a full toolbox … “Functional Analysis of a Model Filamentous Fungus” and that are publicly available at the Fungal Genetics Stock …
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New Vision, New Mission, New Plan: The JGI’s Next Five Years
Research (BER) program. In service of solutions that will impact society, the 2024 strategic plan introduces … milestones. “We will continue to be a user facility that provides genomic capabilities. We specialize in doing … continue to focus on stewardship for the taxpayer money that we are getting, managing our people and resources …
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When “The Blob” Made It Hotter Under the Water
… communities in the ocean drive the biological pump that takes carbon from the atmosphere and keeps it in the … samples. Genomic DNA extracted from the water samples were sequenced by the U.S. Department of Energy (DOE) Joint … their findings in Communications Biology . They reported that the heatwave caused the microbial populations to …
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Year in Review: JGI’s 2018 Progress Report Available Now
… own Jon Bertsch. Microbes isolated from Mono Lake were sequenced by the JGI (isolates here , here and here ), and …
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Streamlining Regulon Identification in Bacteria
… target genes. The Science Regulons are a group of genes that can be turned on or off by the same regulatory protein. … genes of transcription factors, particularly sigma factors that initiate transcription in bacteria. Using this … the 5’-ends by 5’-end sequencing, from which those promoter sequences recognized by a given sigma factor are inferred. …
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Arianna Krinos
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DOE JGI Interns Share Their Summer Experiences
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