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CSP New Investigator Call
The CSP New Investigator Call is for investigators and research initiatives new to the JGI. Projects must be independent of ongoing JGI proposals, and lead PIs cannot have been lead PI … pilot data to assess feasibility of a novel approach or form the foundation for a large-scale CSP proposal …
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JGI@25: The Human Genome Project, or the JGI’s Origin Story
… help solve energy and environmental challenges.   The Human Genome Project began in 1990 when the U.S. Department of … race was being waged. In this JGI@25 video, Susan Lucas, former JGI Production Department Head and current ESnet … Center, JGI staff worked around the clock to generate the sequences of these three chromosomes. In 2004, they …
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Len Pennacchio
In 2003, Dr. Pennacchio joined the DOE Joint Genome Institute and has focused on applying … his Ph.D in 1998 from the Department of Genetics at Stanford University where he uncovered the genetic cause of a … Program Defining the vast landscape of gene regulatory sequences in the human genome. Understanding how variation …
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Better Genome Editing for Bioenergy
… tool that can help scientists engineer organisms for bioenergy applications. Cas9 needs guide RNA to lead it … included researchers at the U.S. Department of Energy Joint Genome Institute (JGI), a DOE Office of Science User … , the scientists thus set out to identify which sgRNA sequences were reliable. In an elegant, quantitative screen, …
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Doubling Down on Known Protein Families
… of scientists at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … unique makeup of microbe players and the functions they perform, artificially replicating a whole community is … the process hinges on referencing to existing genome sequences.  Some of these proteins are what the scientists …
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A Standardized Synthetic Eucalyptus Transcription Factor and Promoter Panel for Re-engineering Secondary Cell Wall Regulation in Biomass and Bioenergy Crops
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JGI@25: Strengthening Soybean
In honor of the JGI's 25th anniversary in 2022, we have … ( Glycine max ) also has the advantage of reducing the need for nitrogen fertilizer. These impressive environmental and energy advantages explain why soybean is a flagship genome of the JGI’s Plant Program.    While soybean has …
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For the Tiniest Archaea, A Genomic Switch of Friend or Foe
… hitchhikers. These organisms are abundant and yet exceptionally small, with mini genomes to match. As a result, they cannot process all of … how these hosts and hitchhikers coexist is key for understanding their impact on wider ecosystems, but …
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Single Cell Research Group
Research in the Woyke laboratory focuses on the utility of single-cell methods to access genetic … material of uncultivated taxa of interest. One such effort is targeted at environmental cells that are from … in the strongly biased representation of sequenced genomes in the public domain, the bulk of which belong to …
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From Sample Shipments to Sequences – A Tour of the JGI’s Sequencing Pipeline
Every year, the JGI sequences around 35,000 samples — from plants, algae, …
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Expanding Virophage Diversity
Virophages are small viruses with double-stranded DNA genomes that co-infect eukaryotic cells along with giant … increased the number of known high quality virophage genome sequences 10-fold through computational approaches. By … & Microbiomes (IMG/M) data suite—which includes  IMG/VR (for Virus)—for the virophage marker gene MCP, they were able …
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Fine-scale evaluation of two standard 16S rRNA gene amplicon primer pairs for analysis of total prokaryotes and archaeal nitrifiers in differently managed soils
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