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DAS Tool for Genome Reconstruction from Metagenomes
… validating an integrated approach to genome recovery from metagenomes. The Science Through the JGI’s Emerging … been utilizing metagenomics as a way to study a collection of hard-to-culture microbes, but the efficacy of this … more genomes from complex metagenomes than any of the single binning tools alone,” primarily because of its …
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Laminarin stimulates single cell rates of sulfate reduction whereas oxygen inhibits transcriptomic activity in coastal marine sediment
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JGI Early Career Researchers Featured in mSystems Special Issue
… In a special issue of mSystems , out May 14, 2019, JGI researchers are among … article, Micro-Scale Applications head Rex Malmstrom and Metagenome Program head Emiley Eloe-Fadrosh outline more … metagenomics. One approach uses fluorescence-activated cell sorting (FACS) to sort cells into several small pools …
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Mining Public Databases Yields Largest Map of Fungal Mitochondrial Genomes to Date
… genome data, unlocking new potential for AI-driven studies of energy metabolism. The Science Researchers produced … inside mitochondria, the energy-producing structures within cells. This is the largest dataset of its kind ever … First, they scanned over 26,000 publicly available metagenomes in the JGI's IMG portal for mitochondrial …
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Measurement Error and Resolution in Quantitative Stable Isotope Probing: Implications for Experimental Design
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DAP-seq Drives Robust Mapping of Gene Regulation
… Multi-species assays yield an unprecedented view of plant evolution and adaptation.    Understanding how … allow simultaneous measurement of multiple samples in a single experiment — and integrated these data with … gene expression maps. Together, the scale of data enabled by these approaches creates a vast resource offering …
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Cell by cell: population genetics in the wild
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Accelerating Metagenomics Discoveries with Deep Learning
… DNA sequencing data gathered from whole samples rather than single cells or isolated strains, is easy to generate, but … insights from metagenomic data. In deep learning, a branch of machine learning, data is passed through algorithms … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science …
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Wrinkles in the rare biosphere: pyrosequencing errors can lead to artificial inflation of diversity estimates
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Virus Discoveries that Keep Getting Bigger
… single-cell work — have quickly accelerated understanding of giant viruses. The Science In the last thirty years, in … viruses. Isolating and co-cultivating these viruses has enabled findings on host range, morphological structures, … reference genome, to sift for snippets of giant viruses in metagenomes. This has been useful in marine environments, …
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Examples: Successful LOIs & Submissions
… See below for examples of successful Letters of Intent to our Community Science Program Large-Scale Call, … to soil carbon storage during simulated range shifts of plant-fungal symbionts … Elucidation of the gene regulatory networks governing terpenoid-mediated … Characterization of simplified soil communities with high and low carbon use …
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JGI@25: Tracking & Subduing the Plague of California’s Oak Woodlands
… In honor of the JGI's 25th anniversary in 2022, we have revisited a … was released to the public in a highly-cited 2006 publication in the journal Science . This provided a … The parallel development of the SODmap Mobile app enabled SOD Blitz participants to geotag specimens they …
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