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Ian Blaby
… eukaryotes. Frontiers in Bioengineering and Biotechnology. 11. 2023 Liu et. al., Bacterial genome editing by coupling Cre-lox and CRISPR-Cas9 systems. PloS one. 15: 11. 2020 Blaby & Cheng, Building a custom high-throughput … for biophotovoltaic energy. Plant biotechnology journal . 14: 1, 22-28. 2016 Blaby et. al., Genome‐wide analysis on …
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Climate Change Threatens Base of Polar Oceans’ Bountiful Food Webs
… microbiomes that influence algal diversity and gene expression. Sailing from pole to pole on four research … an average surface temperature of about 58° Fahrenheit (14° Celsius) — a cool intermediate to the ocean’s extremes … 5th Assessment Report to predict where and how fast the 14° Celsius boundary is moving. “It’s driven by climate: …
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Secondary Metabolites Program
… portion of the biosynthetic gene clusters (BGCs) being expressed. The program works to uncover these hidden … biodesign and metabolomics capabilities to identify, express and characterize bioactive secondary metabolite … analysis, optimization of cell- and cell free-based expression platforms, tools and data for deciphering …
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Examples: Successful LOIs & Submissions
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Natural Prodcast Episode 22: Alison Narayan
… these enzymes allows us to ask the questions which ones express the best in E coli? Which ones are the most thermally … the substrate scope of many enzymes. And so we have limited information. There’s a lot of work to do, and that makes … a great area to operate in, because there’s just so much information that we still need, and that’s the kind of …
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Data Discovery Tool Helps Identify Microbial Roles within Metagenomes
… Neighbor (KNN) Classification. LDA is a supervised data compression technique that was used to take the complex, … of Energy operated under Contract No. DE-AC02-05CH11231. This research used resources of the National Energy … Scientific Computing Center ( https://ror.org/05v3mvq14 ), a DOE Office of Science User Facility under Contract …
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Natural Prodcast Episode 16: Marcy Balunas
… clusters look like.  DAN: For sure.  MARCY: We have so much information about what the Actinomycete biosynthetic gene … when we look at their genomes we don’t get the same kind of information that we would hope for but yet they produce … National Lab. You can find links to transcripts, more information on this episode and our other episodes at  …
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JGI announces 2024 New Investigator portfolio
… in the December 2024 review. You can also find more information about the JGI’s various proposal calls here. …
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What Happens Underground Influences Global Nutrient Cycles
… and the  DOE Joint Genome Institute (JGI)—have selected 11 proposals for support from 53 received through a joint … experiment in the Sierra Nevada mountain range since 2014 to learn more about the microbial responses and feedbacks … JGI since the collaborative science program was formed in 2014 by the Office of Biological and Environmental Research …
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Natural Prodcast Episode 3: The Primer, Part 3
… and it’s a little hard to find in print, but we live in the information age and the ebook version is available at most … dogmas of molecular biology, DNA is the storage medium for information in ourselves and every living thing that we know … we can improve technology, for assembly and cloning and expression, we should be able to actually make the chemical …
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JGI@25: From Life at the Extremes to Editing Genomes
… interest. As Doudna noted in her book, “These bits of information sent a little shiver of intrigue down my spine; … LB et al. Programmed DNA destruction by miniature CRISPR-Cas14 enzymes. Science. 2018 Nov 16;362(6416):839-842. doi: 10.1126/science.aav4294. Harrington LB et al. A thermostable …
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Toward More Reproducible, Reusable Stable Isotope Probing Experiments
… methane and organic matter.  However, to get all of the information that SIP offers, researchers must take on a … generated plenty of insights, many studies don’t report the information needed to reuse and compare data. “So we … around the world, the team have now published a  Minimum Information for any Stable Isotope Probing Sequence (MISIP) …
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