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… Large-scale comparative analysis leads to identification of biosynthetic gene clusters for novel secondary … under laboratory conditions, their genomes can’t be sequenced using traditional approaches. Identifying and … The U.S. Department of Energy Joint Genome Institute, a DOE Office of …

… The joint Critical Minerals and Materials call represents a unique opportunity for researchers to request the capabilities and expertise of both the Joint Genome Institute and the Molecular Foundry … Proposals should be submitted through the Molecular Foundry User …

… An article summarizing the field of viral metagenomics, authored by JGI researchers Lee … hydrothermal vents – and computationally identifying which sequences represent viruses that were present in the sample. … The U.S. Department of Energy Joint Genome Institute, a DOE Office of …

… Interns contributed to a number of projects, from refining lab protocols at the bench to … and Identification of Mitochondrial Plasmids from DNA Sequence Moitrish Majumdar Mentors: Bikash Shrestha, Crysten …

…   Visualizing a novel, candidate viral genome found in the deep … Science Altiarchaea are carbon-fixing microbes and targets of multiple viruses in Earth’s deep subsurface. They are … at virus infections. Their genomes include short DNA sequences that code for CRISPR systems, which help bacteria …

… ActinoBase offers a public portal of insight into special groups of actinobacteria … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility  located at Lawrence … ActinoBase Data Portal … Secondary Metabolite Collaboratory Data Portal …

… Dr. Mouncey joined the DOE Joint Genome Institute in 2017 as the fourth Director in its 27-year history. He has a wealth of managerial experience from almost 20 years in the … Nigel Mouncey is the Secondary Metabolites Program head as well as our JGI Director. …

… Sugarcane was the last major crop without a reference quality … most harvested crop by tonnage, sugarcane accounts for 80% of global sugar production. A reference genome for the … Community Science Program; in 2018, a monoploid reference sequence of sugarcane was published as a step forward in …

… Novel archaeal lineage found in Yellowstone may have been … early Earth conditions. The Science Through a combination of sequencing tools and techniques applied to samples … thousands to millions of copies of a particular DNA sequence from just a few pieces of DNA. Summary The extreme …

… Though visible to the naked eye, microscopy reveals unexpected complexity At first … the slightly murky waters in the tube look like a scoop of stormwater, complete with leaves, debris, and even … the bacterial cells on the molecular level. They amplified, sequenced and assembled the genomes. In parallel, Gros’ lab …

… Virophages are small viruses with double-stranded DNA genomes that … increased the number of known high quality virophage genome sequences 10-fold through computational approaches. By … Integrated Microbial Genomes & Microbiomes (IMG/M) data suite—which includes  IMG/VR (for Virus)—for the virophage …

… Jan. 7: New Capabilities to Study Secondary Metabolism   Although there are still a large number of secondary metabolites yet to be discovered and their … expressing a given BGC in various hosts, availability of sequenced genomes, and computing resources needed to predict …