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Here, There and Everywhere: Large and Giant Viruses Abound Globally
… JGI-led team significantly expands the global diversity of large and giant viruses. While the microbes in a single … 10 times larger. And yet, while they are found everywhere, comparatively little is known about viruses, much less those … encoded functions that could boost host metabolism, such as genes that play roles in the uptake and transport of diverse …
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GenomeOcean Leverages AI to Decode Nature’s Secret Language
… genome discoveries. Unlocking the intricate details of life’s genetic blueprint has long been a significant … analyze but also create DNA sequences mimicking an array of microbial life. By leveraging massive user-generated … Think of verbs and nouns as the nucleotide bases of DNA; genes analogous to paragraphs;  genomes equate to complete …
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Ancient Algae Reveal Secrets of Plant Evolution
… over 600 million years ago. The Science By studying the genes of land plants’ closest algal relative,  Zygnematophyceae , scientists have enhanced our understanding of how early plants transitioned from water to land. Key … Settlement Biomedical Research Enhancement Funds as part of a startup grant of the University of Nebraska Lincoln, …
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An Addiction Crucial to a Fungus’ Reproduction
… A fungus relies on bacteria to regulate key components of its reproductive machinery The Science To better … have on fungal host reproduction, and the reproductive genes they regulate. The bacterial endosymbiont, … , is recognized as a mutualist, where both species of organism benefit from association, but was predicted to …
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The Surprising Structure of a Shrub Willow Sex Chromosome
… A genetic architecture that is characteristic of the sex chromosomes of mammals is, for the first time, seen in a plant. The … found a gene likely responsible for sex determination. Many genes differentiate the shrub willow’s sex chromosomes, so … This work was supported by the NSF Dimensions of Biodiversity Program (DEB-1542509 to S.D., DEB-1542486 to …
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A Better Way to Find RNA Virus Needles in the Proverbial Database Haystacks
… to sift and characterize RNA virus sequences.  A zoo once offered a coloring book featuring polar bears in winter scenes that came with crayons in various shades of white. To researchers searching for sequences of RNA … viral diversity. “Although the technical challenges of data analysis at this scale are formidable.” Computational Sieves …
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Extracting the Secrets of Secondary Metabolites
… survival, may now be easier to characterize following a proof-of-concept study in which researchers paired CRISPR and … because it allows researchers to delete or activate certain genes and assess how these edits affect functionality.  CRAGE allows for the transplanting of these …
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SIPs with Standards
… and even how quickly. But there's a catch: SIP labwork and analysis can be very demanding.  The JGI offers SIP analysis to make these experiments accessible to more …
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JGI@25: Solving the Mystery of the Missing Oil
… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements that showcase our collaborations and … led to the identification of a new “oil-seeking” species related to Oceanospirillales , work that also involved Janet …
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Yasuo Yoshikuni
… Dr. Yasuo Yoshikuni has been head of the DNA Synthesis Science Program since 2015. The mission of this program is to harness the power of DNA synthesis, strain engineering, and biosystems design … at the JGI. Click to learn more about the program's areas of focus, major initiatives and more.  …
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JGI-UC Merced Interns Share Their 2021 Experiences
… During the summer of 2021, 13 interns from UC Merced spent eight weeks working … hone science presentation skills, and participate in professional development enrichment activities. For some … Merced internship program was founded in 2014 with the goal of inspiring students to embark on a career in genomics and …
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Fungus Fuels Tree Growth
… start pinning down how a fungal symbiont spurs growth of poplar, a potential biofuel feedstock.     The Science The fungus  Mortierella … in general; the fungus decreased the expression of poplar genes associated with plant defense (e.g. jasmonic acid and … the Oak Ridge National Laboratory (ORNL) sponsored by the Office of Biological and Environmental Research at the …
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