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Micro-Scale Applications group explores the genetic makeup of natural microbial communities using a variety of … technology in order to enhance the quality of single-cell genomes and directly link functional information with … us to select specific uncultivated microbes for sequencing based on their level of metabolic activity (BONCAT+FACS). To …

… (Graphic: Neil Byers) The JGI launched the 1000 Fungal Genomes (1KFG) Project through a 2012 Community Science … genomes that are both large and complex. The first publication of a genome generated by the OGG initiative — … connect genes and infer changes in gene function across the phylogeny — and link these into our DOE crop plants, so we …

Below is a brief description of the process needed to prepare and ship samples for … requirements for samples submitted to the DOE JGI. Plate-based Preparation Guidelines DNA Preparation Guidelines RNA … Project Manager (PM) a list of organism names (or for metagenomes, sample names).  Need help naming your organisms? …

… enzymes to do chemical reactions. Obviously, in my work, in genome mining, we have an awful lot of crossover, where us … about making them. So I really came at it not necessarily based on the biology really just from as a simple organic … the help of JGI’s DNA synthesis grant. And that having a whole panel of these enzymes allows us to ask the questions …

Analysis reveals cotton genome stability across global lineages . Come harvest time, … Science “The results described in this  Nature Genetics publication will facilitate deeper understanding of cotton … sequencing and computational analysis that enable systems-based scientific approaches to these challenges.  DOE’s …

Biotechnology and the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … de novo, which let the team look at presence/absence of whole genes,” Kellogg agreed. “Getting that information is … sequencing and computational analysis that enable systems-based scientific approaches to these challenges.  DOE’s …

… scientific projects. These solutions include large-scale genome variants analyses, next-generation transcriptome de … assembly, metagenome and metatranscriptome assembly, Hadoop based on sequence analysis framework, etc. For example, this … metagenome binning software … Education … Selected Publications … Software …