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Len Pennacchio
In 2003, Dr. Pennacchio joined the DOE Joint Genome Institute and has focused … his Ph.D in 1998 from the Department of Genetics at Stanford University where he uncovered the genetic cause of a … technical JGI directions for DOE User science. … Complete Publications Genomic Technologies Program Defining the vast …
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JGI@25: Tracking & Subduing the Plague of California’s Oak Woodlands
In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable … energy and environmental challenges.   Scanning the California oak woodlands from the air, large swaths of the … was released to the public in a highly-cited 2006 publication in the journal Science . This provided a …
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A comparative genomics screen identifies a Sinorhizobium meliloti 1021 sodM-like gene strongly expressed within host plant nodules
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Streamlining Regulon Identification in Bacteria
RIViT-seq technology could speed up associating transcription factors with their target genes. … a group of genes that can be turned on or off by the same regulatory protein. Researchers demonstrated the efficacy … regulation is critical to ensuring genes vital for growth and survival across various environments are …
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Tour the IGB
Take a virtual tour of the IGB, home of the DOE Joint Genome Institute. To navigate virtual tours of each … the frontiers of environmental and energy genomics.  For more information about the science depicted, click here …
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Viral Genomics Group
Microbes drive critical ecosystem functions and affect global nutrient cycling, … overview and major challenges of host prediction methods for uncultivated phages.  Current Opinion in Virology .  49 … abundant ocean viruses.  Nature . 537:689-93. … Selected Publications … For further information contact the Group …
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Expression and regulatory asymmetry of retained Arabidopsis thaliana transcription factor genes derived from whole genome duplication
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Taking Stock of the Known and Unknown Microbial Space
Metagenomic datasets could help map out microbial diversity … the microbial diversity we know about, and proposes a path forward to curate and cultivate what is still unknown.  “We … of the available datasets. Efforts to recover MAGs by extracting data directly from environmental samples over the …
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High‐throughput identification of novel heat tolerance genes via genome‐wide pooled mutant screens in the model green alga Chlamydomonas reinhardtii
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JGI@25: From Life at the Extremes to Editing Genomes
In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable … Congratulations to Jennifer Doudna of the University of California (UC), Berkeley and Lawrence Berkeley National … nature was using it to do something important.” Related Publications:  A scoutRNA Is Required for Some Type V …
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acCRISPR: an activity-correction method for improving the accuracy of CRISPR screens
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Evolution of a Fungal Gene Expression Regulator
Describing the largest analysis to date of the modified DNA base 5mC variations in fungi. The Science Changing an A, … ways to protect poplar and other crops being considered for bioenergy feedstock development. Summary With the aim of …
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