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Rapid selective sweep of pre-existing polymorphisms and slow fixation of new mutations in experimental evolution of Desulfovibrio vulgaris
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The genome of Syntrophorhabdus aromaticivorans strain UI provides new insights for syntrophic aromatic compound metabolism and electron flow
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New Biological Insights Into How Deforestation in Amazonia Affects Soil Microbial Communities Using Metagenomics and Metagenome-Assembled Genomes
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Sequence-based bioprospecting of myo-inositol oxygenase (Miox) reveals new homologues that increase glucaric acid production in Saccharomyces cerevisiae
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2024 Progress Report
… secondary users who made use of our data. We completed 39,870 projects in FY24 We generated 871 Terabases of sequence We synthesized 9.7 Megabases of … and cell-free expression platforms.  … We closed our 2018 Strategic Plan at the end of September, 2023 with over 90% …
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Natural Prodcast Episode 3: The Primer, Part 3
… of molecular biology got more sophisticated around the 80s and the 90s. And so we started to be able to explore DNA …
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Natural Prodcast Episode 11: Marnix Medema
… then I contacted a number of PIs, and in the end, I think 80 research groups from around the world contributed with, … are living inside the roots. And from that we got around 800 biosynthetic gene clusters, many of them full length. …
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Natural Prodcast Episode 5: Brad Moore
Brad: Yeah, for sure. So we’re going back to the mid-late ’80s. And at that time, you know, it’s before genomics … synthesis, the area of discovery, was just budding in the 80s. So that was pretty special. And for someone like …
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Metagenome Program
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Natural Prodcast Episode 20: Brian Bachmann
And I thought, well, I know that we can do this. So in 2006 was when I started our cave-based natural product …
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Natural Prodcast Episode 23: Aaron Puri
… learn as much about it as possible starting with we picked 183 of them. And we sent that list to the Joint Genome … an unusual acyl-homoserine lactone signal . mBio. 2023 Aug 31;14(4):e0101023. doi: 10.1128/mbio.01010-23. Publication: Cummings DA Jr. Methylotroph …
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IMG-ABC: new features for bacterial secondary metabolism analysis and targeted biosynthetic gene cluster discovery in thousands of microbial genomes
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