Search

… that you do, then it’s very easy to think that, OK, I find 25 gene clusters, there must be 25 new compounds. Or everything that has similarity to a gene … that I was exchanging with people. So I think I wrote 3,000 emails in the course of one and a half year while …

… because I was always swimming or surfing. And you know, 25 hours a day we’re at the beach practically. It was just – … has been a lot of fun for us in recent years. Started in 2015, when two things happened. One, a new graduate student … domoic acid, [and] caused amnesic shelfish poisoning. Over 100 million dollars was lost just in the Dungeness crab …

… went on to work at a groundbreaking company in the early 2000s called Ecopia, which was a very early genome mining … just did a low-resolution shotgun pass where we sequenced 500 runs. And then we used those to find gene clusters in … https://sim.confex.com/sim/np2023/meetingapp.cgi/Paper/46926 Jen Wurm:  …

… 2021 Aug 20;16(8):1332-1338. doi: 10.1021/acschembio.1c00329. …

… who was working on these things in the very early 1900s.  DAN: And so he has drawn what he called … from 1940 to 2000. As you can see, from the 1940s, into the 50s into the 60s, there was a huge growth – a huge explosion …