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Connecting chemical and protein sequence space to predict biocatalytic reactions
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Boosting Small Molecule Production in Super “Soup”
… Yeast strains engineered for the biochemical conversion of glucose to value-added products are limited in chemical … format for chemical synthesis in the absence of cell growth by isolating the soluble components of lysed cells. By … to increase the productivity rates for pathways of varying complexity. Rasor cautioned that further optimization is …
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The genome of the polyextremophilic yeast, Naganishia friedmannii, reveals adaptations involved in stress response pathways, carbohydrate metabolism expansion, and a limited DNA repair repertoire
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A Revamped Amplification Method that Enables Nearly Complete Single-Cell Genomes
… from single cells. The Science Studying the  genomes of microorganisms is incredibly useful for understanding the microbiome of the earth, but most species do not grow easily in the … usually employ two different methods; shotgun metagenomic sequencing and single-cell sequencing. For years, extracting …
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Complete Genome Sequence for Asinibacterium sp. Strain OR53 and Draft Genome Sequence for Asinibacterium sp. Strain OR43, Two Bacteria Tolerant to Uranium
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Wrinkles in the rare biosphere: pyrosequencing errors can lead to artificial inflation of diversity estimates
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How to Target a Microbial Needle within a Community Haystack
… A workflow for capturing the genetic make-up of specific uncultivated microbes from complex environmental samples. The Science A team led by researchers at the Max Planck Institute (MPI) for Marine … to just over 50 percent of the targeted metagenome sequence reads. This demonstrates the viability of HCR-FISH+FACS for …
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Two new high-resolution crystal structures of carboxysome pentamer proteins reveal high structural conservation of CcmL orthologs among distantly related cyanobacterial species
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Defining the Sphagnum Core Microbiome across the North American Continent Reveals a Central Role for Diazotrophic Methanotrophs in the Nitrogen and Carbon Cycles of Boreal Peatland Ecosystems
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Combating a Global Threat to a Clonal Crop: Banana Black Sigatoka Pathogen Pseudocercospora fijiensis (Synonym Mycosphaerella fijiensis) Genomes Reveal Clues for Disease Control
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Exploring Proteomes of Robust Yarrowia lipolytica Isolates Cultivated in Biomass Hydrolysate Reveals Key Processes Impacting Mixed Sugar Utilization, Lipid Accumulation, and Degradation
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The Power of One, Amplified
… A preview of how large-scale single cell genomics complements … the value of conducting large-scale single cell genomics by collecting nearly 500 single cells from a single low … value to the other commonly used culture-independent sequencing approaches including amplicon and metagenomic …
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