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Ian Blaby
Since 2019 Dr. Blaby heads the DNA synthesis platform at the Joint … with a view to developing a deeper understanding of sequence-based gene function. … B.Sc. (HONS) – University of … tool for targeted and genome-scale gRNA design and sequence extraction for prokaryotes and eukaryotes. …
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Doubling Down on Known Protein Families
… big the room is.  A new study  published online Oct. 11, 2023 in  Nature highlights the vast array of functional … the process hinges on referencing to existing genome sequences.  Some of these proteins are what the scientists … artificial intelligence to decode the language of protein sequences and obtain hints of their possible functions. Yet …
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A Collaboration to Improve Plant Genome Annotations Across Species
Schmutz is the Plant Program Lead at the JGI. Sarah:  Why is a resource like this important to the field of plant … plants did you all look at? Avinash: We started off with 12 plants, which are JGI Flagship Plants, mostly related to … we are looking at 18 different species, which included over 2000 RNA Seq libraries. As I previously mentioned, this is …
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Here, There and Everywhere: Large and Giant Viruses Abound Globally
… genomes of uncultivated giant viruses from environmental sequences across the globe, then using these sequences to make inferences about the biogeographic … out and characterize uncultivated viruses. For instance, a 2018 study from a JGI-led team uncovered giant viruses in …
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Nigel Mouncey
Dr. Mouncey joined the DOE Joint Genome Institute in 2017 as the fourth Director in its 27-year history. He has a wealth of managerial experience from almost 20 years in the Industrial Biotechnology private sector, as …
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JGI@25: Tracking & Subduing the Plague of California’s Oak Woodlands
In honor of the JGI's 25th anniversary in 2022, we have revisited a number of … of millions of trees in California alone. With the genome sequence in hand, the UC team led the charge to develop … … Publication: Tyler BM et al. Phytophthora genome sequences uncover evolutionary origins and mechanisms of …
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You Can Move, But You Can’t Hide
MGEs based upon their gene content and their genetic sequences. The software was created by researchers under the … Science User Facilities operated under Contract No. DE-AC02-05CH11231. This work also received support from the Genomic …
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A Complex Confection Decoded: Sugarcane Reference Genome
… partly enabled by the JGI’s Community Science Program; in 2018, a monoploid reference sequence of sugarcane was published as a step forward in … .   … The work (proposal: https://doi.org/10.46936/10.25585/60001084 and …
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10 From JGI on the 2019 Highly Cited Researchers List
… the IP & Science arm of Thomson Reuters, has released their 2019 list of Highly Cited Researchers , which includes 10 affiliated with the JGI . The 2019 list focused on Highly Cited Papers, defined in the … Nature Genetics, the work is part of a long-term project to sequence, annotate and analyze the genomes of more than 300 …
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Plotting a Model for Virus-Host Warfare Deep Below Ground
… at virus infections. Their genomes include short DNA sequences that code for CRISPR systems, which help bacteria … resist foreign genetic elements by incorporating short sequences from infecting viruses and phages. In these … do so, they compared samples collected from an aquifer in 2012 and 2018 against a biofilm sample collected in 2018. …
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Uncovering Novel Genomes from Earth’s Microbiomes
… under laboratory conditions, their genomes can’t be sequenced using traditional approaches. Identifying and … in a wide range of research fields. A public repository of 52,515 microbial draft genomes generated from environmental … of metagenome-assembled genomes (MAGs) directly from sequenced environmental samples without needing to cultivate …
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Climate Change Threatens Base of Polar Oceans’ Bountiful Food Webs
… are.” But according to a new study published September 16, 2021 in Nature Communications , warmer waters and … than previously suspected. “That would cause significant consequences on the entire food web, and therefore ecosystem … After isolating the algal communities on filters, they sequenced DNA ‘marker’ gene sequences to identify the …
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