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… they had the same conserved polyketide synthase and then P3. We still don’t know why 20 years later. JACKIE WINTER: … anybody in natural product discovery in any field and even 30 years ago would say it’s the [key to] success. And that … by chemical synthesis and make analogs in combination of mutagenesis and direct evolution. Yeah. DAN UDWARY: So it’s …
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Metagenome-assembled archaeal genomes provide new insights … they mined the Integrated Microbial Genomes & Microbiomes (IMG/M) database maintained by the U.S. Department of Energy … the oldest metabolisms, with the first traces possibly at ~3.5 Gy (billion years),” Borrel and Gribaldo said in an …
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