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The fungus that made itself at home
… By comparing genetic information from similar organisms, researchers have gained insights on why the dry rot ( Serpula … capacity to damage the wood in homes, bioenergy researchers have been interested in harnessing the brown rot … of the wood blocks than its partner brown rots. The team’s results reflect the evolutionary gains and losses of S. …
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A Revamped Amplification Method that Enables Nearly Complete Single-Cell Genomes
… scientists are now getting more complete genomic results from single cells. The Science Studying the  genomes … invested in being the bridge to help scientists and researchers achieve their analysis goals. Offering this tool … genome is missing from the final assembly. So while researchers are confident all the DNA sequences came from one …
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Building Sphagnum Genomic Resources
… Sphagnome data would enable researchers’ insights on their potential carbon cycling … Enabled by the JGI’s Community Science Program (CSP), researchers are developing a number of resources to build up … act as a carbon sink or a carbon source. These research results, building on the availability of genomic information …
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Streamlining Regulon Identification in Bacteria
… can be turned on or off by the same regulatory protein. Researchers demonstrated the efficacy and potential of regulon … and unscalable. To test the efficacy of RIViT-seq, researchers recently characterized 12 sigma factors and were … had been experimentally verified in S. coelicolor . With results from the research, RIViT-seq data have increased the …
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An Automated Tool for Assessing Virus Data Quality
… CheckV can help researchers assess virus sequence fragments and data quality. … viruses. Following up on those guidelines, JGI researchers have now developed CheckV (pronounced “Check-Vee”) … viral genomes from metagenomes is challenging and often results in highly fragmented data, which limits the ability …
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First Monoploid Reference Sequence of Sugarcane
… the highly polyploid sugarcane, an international team of researchers has successfully assembled a first monoploid … of the world’s sugar, which is of interest to bioenergy researchers who want to develop sustainable alternative fuels. … regions in sorghum. Based in part on these positive results, in 2017, JGI approved a CSP proposal from the …
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A Collaboration to Improve Plant Genome Annotations Across Species
… As part of that partnership, the JGI and HudsonAlpha researchers led a team that  recently published work on the JGI Plant Gene Atlas in  Nucleic Acids Research . The project spans 15 years and involves more than … did so by analyzing this huge sample set specifically using results from tissue and condition-specific expression …
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The Surprising Structure of a Shrub Willow Sex Chromosome
… (DOE). (Poplar is a Flagship Plant.) To engineer them, researchers need to select and breed cultivars for the next … understand how sex determination works in shrub willow, researchers investigated the structures of the sex chromosomes … the repetitive areas of the complete sex chromosomes. The results were published in  Genome Biology . The team found …
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Gut Fungi: Unexpected Source of Novel Chemicals
… at Pacific Northwest National Laboratory. The team’s research at both the JGI and EMSL was enabled by the … for User Science (FICUS) initiative, which allows researchers to more easily integrate the expertise and … up the compounds and to puzzle out their structures. Their results indicate that anaerobic fungi synthesize molecules …
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How Maize Makes An Antibiotic Cocktail
… entailing the function of more than a dozen enzymes. But researchers have now revealed that just a handful of enzymes … giving scientists a bigger bang for their buck. The research team reports that transferring just four genes … clusters on different maize chromosomes. The collective results demonstrate that the zealexin pathway is a critical …
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Innovative Technology Improves Our Understanding of Bacterial Cell Signaling
… gut. To better understand the dynamics of this molecule, researchers developed the first chemiluminescent biosensors … wider range of environments. This new technology enables researchers to directly measure cyclic di-GMP levels in … part by a proposal to the DNA Synthesis CSP call , and the results are described in ACS Chemical Biology. Using …
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RECAP: Keynote Speakers Talk Innovation at 2022 JGI Annual Meeting
… the CRISPR-Cas9 investigations began as “curiosity driven research.” In the early 2000s, UC Berkeley colleague and … Doudna said during her keynote. In 2012, Doudna published results indicating how CRISPR Cas-9 could be used as a DNA … to address a wide range of new questions — from basic research, like learning how to optimize the gene editing …
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