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Plant-Microbial Interactions Group
… single-cell and spatial transcriptomics barcode-based genetics (RB-TnSeq), and computational genomics to better … experimental characterization methods, in addition to bioinformatics tools to elucidate phage function in this … of plant/environmental responses … Selected Publications … Research Team Alumni … For further details, …
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Enlarging Windows into Understanding Gene Functions
JGI innovates protocol revealing how genetic variations in sequences affect traits. In a text … array of combinations, are unremarkable, save perhaps for the absence of all the other letters of the alphabet. … genes are turned on is known as DNA affinity purification sequencing or DAP-seq. The technology was developed by Ronan …
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Offerings & Capabilities
… cutting-edge capabilities to help advance their science by generating data in three overarching categories: Sequencing, Synthesis and Metabolomics. Strong internal …
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PCR and Omics Based Techniques to Study the Diversity, Ecology and Biology of Anaerobic Fungi: Insights, Challenges and Opportunities
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User Support Analysis Group
User Support Analysis group provides computational analysis for new technology development and JGI user science … analysis for diverse experiment types, with main focus areas being genome variation, transcriptomics and … development of automated analysis pipelines for standard sequencing products performed at scale. Our group also …
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Evolution of a Fungal Gene Expression Regulator
… ways to protect poplar and other crops being considered for bioenergy feedstock development. Summary With the aim of … that unlike most flowering plants and animals, fungi lack gene body methylation. The analysis revealed that 5mC in … specific 5mC methyltransferase (MTase) variants. Using new sequencing technologies for producing both reference genomes …
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Environmental Genomics Group
… approaches to identify and characterize genomic information from uncultivated microbes and viruses. We develop … Ladau, J. et al. (2019)  Spatial, Temporal, and Phylogenetic Scales of Microbial Ecology . Trends Microbiol. … Microbiology , 15032. 10.1038/nmicrobiol.2015.32 … Selected Publications … For further details, please reach out to the …
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Viral Genomics Group
… overview and major challenges of host prediction methods for uncultivated phages.  Current Opinion in Virology .  49 … 4 , 1895–1906 Roux, S. et al. (2019) Minimum Information about an Uncultivated Virus Genome (MIUViG).  … abundant ocean viruses.  Nature . 537:689-93. … Selected Publications … For further information contact the Group …
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Microbial Community Analyses Inform Geochemical Reaction Network Models for Predicting Pathways of Greenhouse Gas Production
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From Intern to Published Scientist: The Journey of a JGI-UC Merced Intern
For many scientists, the culmination of their work into a … current PhD student, reached this milestone with a recent publication in Molecular Biology and Evolution . “It’s my … a quest to better understand the factors and mechanics of gene expression in over 400 fungi species. “Fungi are the …
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Guidelines for public database submission of uncultivated virus genome sequences for taxonomic classification
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Synthetic Biology Lab
… technologies to the broader community.  We focus our efforts on integrating database mining and sequence design … We also develop methods for efficient QA/QC based on next-generation sequencing technologies including PacBio and Illumina.  The …
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