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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
… have made strides in improving and applying a method that allows researchers to quickly modify diverse bacterial genomes. In 2019, the JGI’s Yasuo Yoshikuni and … CRAGE, JGI has established a portfolio of microbial hosts that users can select to be engineered. “Piloting access to …
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Genome-centric view of carbon processing in thawing permafrost
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Boosting Small Molecule Production in Super “Soup”
… of Northwestern University describe a two-pronged approach that starts with engineered yeast cells but then moves out … senior authors. “But this has been done most commonly in bacterial-based systems, and so one of the things that I … CRISPR-Cas9 that enhanced their ability to redirect the carbon in the cells toward particular pathways. In this …
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Prevalent genome streamlining and latitudinal divergence of planktonic bacteria in the surface ocean
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Hiroshi Otani
… and implementing new technologies and methodologies that facilitate discovery of new secondary metabolites. Prior to joining the JGI, he studied … Mol. Microbiol. 87, 1223-1236. PubMed … Education … Publications …
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Dinoflagellates alter their carbon and nutrient metabolic strategies across environmental gradients in the central Pacific Ocean
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Niche differentiation of bacteria and fungi in carbon and nitrogen cycling of different habitats in a temperate coniferous forest: A metaproteomic approach
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Drought re-routes soil microbial carbon metabolism towards emission of volatile metabolites in an artificial tropical rainforest
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Diversity and population structure of Marine Group A bacteria in the Northeast subarctic Pacific Ocean
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Exploring novel alkane-degradation pathways in uncultured bacteria from the North Atlantic Ocean
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Ecology of inorganic sulfur auxiliary metabolism in widespread bacteriophages
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A dynamic microbial sulfur cycle in a serpentinizing continental ophiolite
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