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Who We Are
…   The U.S. Department of Energy (DOE) Joint Genome Institute (JGI) is a national user facility … The U.S. Department of Energy (DOE) Joint Genome Institute (JGI) is a … and technology development pioneered at the U.S. DOE genome centers at Lawrence Berkeley National Laboratory , …
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JGI@25: Using Team Science to Build Communities Around Data
… (Graphic: Neil Byers) The JGI launched the 1000 Fungal Genomes (1KFG) Project through a 2012 Community Science … genomes that are both large and complex. The first publication of a genome generated by the OGG initiative — … Plants . C-fern has a genome approximately three times the size of the human genome. There are four more fern genomes …
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JGI@25: A Single Cell, Myriad Microbial Discoveries
… In honor of the JGI's 25th anniversary in 2022, we have revisited a … quantities of DNA derived from individual environmental cells. The proof of principle study built off earlier … year, the JGI team reported the first closed and finished genome derived from an uncultured bacterial single cell – a …
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Ancient Algae Reveal Secrets of Plant Evolution
… land. Key gene groups involved in stress tolerance and multicellularity enabled plants to develop complex structures and … in sustainable agriculture and clean energy. These evolutionary strategies that helped plants thrive under … Program of the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User …
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Community Science Program
… community at large with access to high-throughput sequencing, synthesis, and metabolomics at the JGI for projects of relevance to Department of Energy (DOE)  Mission Areas . Through this program, the DOE aims to advance genome science-based scientific research from a broad range …
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Innovative Technology Improves Our Understanding of Bacterial Cell Signaling
… is found in nearly all types of bacteria and interacts with cell signaling networks that control many basic cellular … at the University of California, Berkeley and the Joint Genome Institute, a DOE Office of Science User Facility, … as candidate biosensors. These 92 homologues were synthesized as codon optimized sequences and cloned into the …
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Picking Up Threads of Cotton Genomics
… Analysis reveals cotton genome stability across global lineages . Come harvest time, … approximately 2.3 billion bases or Gigabases (Gb) in size, and are hybrids comprised of cotton A and cotton D … Science “The results described in this  Nature Genetics publication will facilitate deeper understanding of cotton …
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A Natural Mechanism Can Turbocharge Viral Evolution
… Understanding how a fundamental mechanism of evolution allows microbes to adapt to changing environments. … step in the deadly dance between a virus and microbial cell is an embrace. For a virus with a “head-tail” … ago, a team discovered a group of viruses that had in their genomes a surprising tool: a “diversity generating …
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Len Pennacchio
… In 2003, Dr. Pennacchio joined the DOE Joint Genome Institute and has focused on applying state-of-the-art molecular methods to address wide-ranging … joint appointments as a Deputy Director at the DOE Joint Genome Institute, Senior Scientist at Lawrence Berkeley …
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Viruses Reprogram Cells into Different Virocells
… Microbial cells infected by viruses undergo metabolic reprogramming. … from The Ohio State University and the University of Michigan studying how virus infections cause significant … between the  U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User …
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JGI@25: Strengthening Soybean
… and energy advantages explain why soybean is a flagship genome of the JGI’s Plant Program.    While soybean has … the way, it was just like rediscovering genetics, with the evolution of sequencing technologies and the evolution of … — most fungi are around 50 million Mb, or megabases, in size). So, the JGI helped a consortium of researchers from …
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Tracing the Evolution of Shiitake Mushrooms
… New genomes highlight the diversity of white rot fungi in the … decomposers that can break down all of wood’s components — cellulose, hemicellulose, and the toughest molecule, lignin. Understanding Lentinula genomes and their evolution could provide strategies for converting plant …
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